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Table 1 Demographic data of 19 randomized patients (mean or number are noted, standard deviations are in parentheses) at Day 0 (D0)

From: Are paraspinous intramuscular injections of botulinum toxin a (BoNT-A) efficient in the treatment of chronic low-back pain? A randomised, double-blinded crossover trial

Patients Botulinum toxin Placebo t-test (p)
Sample size N = 9 N = 10  
Men/Women 3/6 0/10 0.047
Age: mean (SD) in years 38.1 (5.94) 38.2 (10.27) 0.49
Spinal pain intensity: mean (SD) /100 mm 59.33 (15.71) 58.70 (15.89) 0.47
Radicular pain intensity: mean (SD) /100 mm 42.89 (26.98) 28.40 (27.16) 0.13
Pain intensity during last month: mean (SD) /100 mm 63.11 (25.70) 66.70 (24.50) 0.38
Pain intensity during last week: mean (SD) /100 mm 67.67 (22.37) 57.50 (25.63) 0.18
Quebec initial score mean (SD) /100 mm 52.56 (11.64) 51.70 (16.55) 0.45
Disability during last 8 months: mean (SD) /100 mm 58.22 (82.29) 151.6 (96.56) 0.018
Disability during last month: mean (SD) /100 mm 7.44 (12.99) 13.4 (14.55) 0.18
Quality of life at inclusion: mean (SD) /100 mm 76.56 (16.41) 65.00 (17.80) 0.08
Number of days with painkillers or anti-inflammatories: number (SD) 19.67 (13.44) 14.1 (12.57) 0.18
Paravertebral painful point pressure Right/Left/Bilateral 4/3/2 4/0/6  
Stiffness: number 8 6 0.08
Tendency to cough: number 5 7 0.27
Instability: number 9 8 0.08
Schober’s test: centimeter (SD) 4.22 (1.30) 3.95 (1.77) 0.35
Hand-ground distance: centimeter (SD) 28.60 (13.60) 20.60 (15.60) 0.13
Spinal pain: mean (SD) 3.13 (1.46) 3.60 (1.84) 0.27
Paravertebral pain: number 2 5 0.33
Lasegue sign: number 0 0  
Pseudo-Lasegue sign: mean (SD) 0.25 (0.46) 0.5 (0.53) 0.15
Disco-radicular conflict: number 0 1 0.17
MODIC L1-L2 0/1/2/3 9/0/0/0 9/0/1/0 0.17
MODIC L2-L3 0/1/2/3 9/0/0/0 9/0/1/0 0.17
MODIC L3-L4 0/1/2/3 9/0/0/0 9/0/1/0 0.17
MODIC L4-L5 0/1/2/3 9/0/0/0 9/0/0/1 0.17
MODIC L5-S1 0/1/2/3 5/3/1/0 4/3/2/1 0.15
HADAR L1-L2 0/1/2/3 8/1/0/0 8/2/0/0 0.31
HADAR L2-L3 0/1/2/3 6/3/0/0 7/3/0/0 0.44
HADAR L3-L4 0/1/2/3 4/5/0/0 7/1/2/0 0.33
HADAR L4-L5 0/1/2/3 1/6/2/0 3/4/3/0 0.37
HADAR L5-S1 0/1/2/3 1/4/4/0 0/4/6/0 0.18
Isokinetic maximum strength: n/m (SD) 115.33 (58.63) 114.44 (37.63) 0.49
Isokinetic endurance: n/m (SD) 89.11 (62.50) 77.33 (53.86) 0.34
Flexors/extensors ratio at 60°: % (SD) 123.63 (37.56) 119.36 (49.51) 0.42