Fig. 5

Gene expression of ADAMTS-5 and -9 mRNA. a: The time-response of ADAMTS-5 mRNA to Hb. Human synovial cells were cultured in the presence or absence of Hb (100 μg/ml). There were no significant differences between control and Hb treatment groups at each time. b: The time-response of ADAMTS-9 mRNA to Hb. ADAMTS-9 mRNA expression was significantly higher at 12 and 24 h after Hb stimulation. (p < 0.05)