Skip to main content
Fig. 4 | BMC Musculoskeletal Disorders

Fig. 4

From: Hemoglobin stimulates the expression of ADAMTS-5 and ADAMTS-9 by synovial cells: a possible cause of articular cartilage damage after intra-articular hemorrhage

Fig. 4

ELISA analysis for time-course study of ADAMTS-5 and -9 produced by cultured human synovial cells. a: ELISA analysis for the time-course response of ADAMTS-5 to Hb. Confluent cells were incubated with or without Hb (100 μg/ml), then the conditioned media were collected at 6, 12, and 24 h. The level of ADAMTS-5 showed time-course dependency, and there was significantly higher expression at 6, 12, and 24 h after Hb stimulation (p < 0.05). b: ELISA analysis for the time-course response of ADAMTS-9 to Hb. ADAMTS-9 was highly expressed at 6, 12, and 24 h significantly after Hb stimulation compared with the control. (p < 0.05)

Back to article page