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Table 2 Table showing semi quantitatively the magnitude of expressions for TNFR1 and TNFR2 immunoreactions (IR)

From: Bilateral muscle fiber and nerve influences by TNF-alpha in response to unilateral muscle overuse – studies on TNF receptor expressions

  Animals showing normal morphology TNF Receptor type 1 Animals showing normal morphology TNF Receptor type 2 Animals expressing myositis TNF Receptor type 1 Animals showing myositis TNF Receptor type 2
Abnormal muscle fibers - - ++ -
Necrotic muscle fibers with invading cells - - - ++
Muscle nuclei - +++ - +++
White blood cells - - + +++
NMJ - +++ - +++
Nerve fascicles (+) (+) ++ ++
  1. – (no reaction), (+) (very limited reaction, + (moderate reaction), ++ (marked reaction), +++ (very marked/regularly occurring reaction). The animals for which a clear myositis was seen (related to most animals from groups 4 and 6 and sometimes those from group 5) and for which a normal muscle morphology occurred (related to animals from groups 1–3 and occasional animals from group 5)