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Fig. 8 | BMC Musculoskeletal Disorders

Fig. 8

From: Bilateral muscle fiber and nerve influences by TNF-alpha in response to unilateral muscle overuse – studies on TNF receptor expressions

Fig. 8

TNFR1 IR expression in the cytoplasm of muscle fibers, the reactions showing a finely spread and dot-like pattern (a, b) (arrowheads). Sample from 6 week group, contralateral side (arrows at unstained areas). c and d show a much destroyed necrotic muscle fiber (asterisks) partly being infiltrated by white blood cells TNFR2 IR (c) preabsorption with TNFR2 antigen in (d). The white blood cells express TNFR2 IR. Sample from experimental animal (3 week group, contralateral side). e shows another example of muscle fiber being infiltrated by white blood cells and being stained with H&E in a specimen from experimental animal (6 week group, contralateral side). Orig.magnif. ×500 (a), ×300 (c-e)

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