Table 3 General pattern of neuroimmune expression
From: Neuroimmune expression in hip osteoarthritis: a systematic review
| Â | Sinovial Fluid | Synovial Membrane | Cartilage | Serum | Immune Cells | Blood | Bone |
|---|---|---|---|---|---|---|---|
Increased | IFN-γ IL-6 MCP-1 MIP-1β VEGF | IL-10 IL-1α IL-8 TNF- α TGF-β1 TGF-β2 TGF-β3 CGRP NF-Kb TuJ-1 SP | IL-10 IL-1α TNF- α TGF-β1 TGF-β2 TGF-β3 | TNF- α | BAFF GM-CSF IFN-γ IL-2 | IL-6 OPG TNF- α | BMP-1 BMP-6 ICAM ICAM-3 IL-6 IL-8 PGE-2 TGF-β1 TGF-β2 TGF-β3 |
Doubtful or Equal |  |  | IL-8 Il-1β |  |  |  | Il-1β TGF-β TGF-βR1 TNF- α |
Decreased | IL-1Rα Il-1β PDGF-ββ RANTES TNF-α |  |  | IL-8 | IL-10 IL-4 IL-6 TNF- α | IL-10 IL-1α RANKL | BMP-5 GM-CSF IFN-γ IL-10 IL-12 IL-1α IL-2 IL-4 IL-5 VEGF-b VEGF-c |