Table 3 Methylation rate in the promoter region of selected genes
From: Analysis of DNA methylation in chondrocytes in rats with knee osteoarthritis
Target genes (distance to the initiationcodon) | sham group | KOA group | P value |
|---|---|---|---|
Methylation rate (mean ± SD) | |||
C/ebpα-2 (−452 bp) | 0.01096 ± 0.0043 | 0.002572 ± 0.0024 | 0.005 |
Cdk2 (−55 bp) | 0.013573 ± 0.0052 | 0.004166 ± 0.0030 | 0.008 |
Bak1 (6452 bp) | 0.026212 ± 0.0139 | 0.007123 ± 0.0058 | 0.022 |
Fas | 0.958532 ± 0.0063 | 0.944658 ± 0.0096 | 0.047 |