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Table 2 Factors influencing functional disability (total HAQ-DI score ≥ 0.5 as median) in patients with RA (n = 120)

From: Impact of midfoot and Hindfoot involvement on functional disability in Korean patients with rheumatoid arthritis

Variables Unadjusted analysis Adjusted analysis
OR (95% CI) P value OR (95% CI) P value
Age 1.00 (0.97–1.03) 0.87 1.01 (0.97–1.05) 0.78
Disease durationa 2.25 (1.02–4.99) 0.05 1.85 (0.59–5.86) 0.29
BMI 1.05 (0.95–1.16) 0.37 1.03 (0.90–1.17) 0.71
DAS28-ESRb 6.34 (2.79–14.40) <0.05 4.33 (1.69–11.10) <0.05
RF positive 2.67 (0.87–8.22) 0.09 2.34 (0.64–8.64) 0.20
Glucocorticoid 1.70 (0.74–3.88) 0.21 2.09 (0.67–6.58) 0.19
Biologic DMARDs 3.76 (1.65–8.56) 0.00 1.58 (0.51–4.92) 0.43
RA involvement
 Forefoot 0.91 (0.41–2.05) 0.83 1.03 (0.39–2.71) 0.95
 Midfoot 4.68 (1.62–13.60) <0.05 2.02 (0.49–8.29) 0.33
 Hindfoot 4.66 (2.07–10.5) <0.05 3.14 (1.18–8.38) <0.05
 Ankle 0.93 (0.13–6.85) 0.95 0.68 (0.06–7.70) 0.75
Foot deformity
 Hallux valgus 1.67 (0.69–4.06) 0.26 1.03 (0.32–3.33) 0.96
 Metatarsus primus varus 1.06 (0.49–2.29) 0.89 1.09 (0.41–2.88) 0.87
 Pes planus 2.22 (0.39–12.60) 0.37 1.30 (0.15–10.90) 0.81
  1. BMI body mass index, DAS28 disease activity score 28, DMARDs disease-modifying antirheumatic drugs, ESR erythrocyte sedimentation rate, HAQ-DI Health Assessment Questionnaire-Disability Index, OR odds ratio, RF rheumatoid factor
  2. aDisease duration was divided into two groups based on a cut-off of 2 years
  3. bDAS28-ESR was divided into two groups, remission to low disease activity (DAS28-ESR ≤ 3.2) and moderate to high disease activity (DAS28-ESR > 3.2)