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Table 2 Factors influencing functional disability (total HAQ-DI score ≥ 0.5 as median) in patients with RA (n = 120)

From: Impact of midfoot and Hindfoot involvement on functional disability in Korean patients with rheumatoid arthritis

Variables

Unadjusted analysis

Adjusted analysis

OR (95% CI)

P value

OR (95% CI)

P value

Age

1.00 (0.97–1.03)

0.87

1.01 (0.97–1.05)

0.78

Disease durationa

2.25 (1.02–4.99)

0.05

1.85 (0.59–5.86)

0.29

BMI

1.05 (0.95–1.16)

0.37

1.03 (0.90–1.17)

0.71

DAS28-ESRb

6.34 (2.79–14.40)

<0.05

4.33 (1.69–11.10)

<0.05

RF positive

2.67 (0.87–8.22)

0.09

2.34 (0.64–8.64)

0.20

Glucocorticoid

1.70 (0.74–3.88)

0.21

2.09 (0.67–6.58)

0.19

Biologic DMARDs

3.76 (1.65–8.56)

0.00

1.58 (0.51–4.92)

0.43

RA involvement

 Forefoot

0.91 (0.41–2.05)

0.83

1.03 (0.39–2.71)

0.95

 Midfoot

4.68 (1.62–13.60)

<0.05

2.02 (0.49–8.29)

0.33

 Hindfoot

4.66 (2.07–10.5)

<0.05

3.14 (1.18–8.38)

<0.05

 Ankle

0.93 (0.13–6.85)

0.95

0.68 (0.06–7.70)

0.75

Foot deformity

 Hallux valgus

1.67 (0.69–4.06)

0.26

1.03 (0.32–3.33)

0.96

 Metatarsus primus varus

1.06 (0.49–2.29)

0.89

1.09 (0.41–2.88)

0.87

 Pes planus

2.22 (0.39–12.60)

0.37

1.30 (0.15–10.90)

0.81

  1. BMI body mass index, DAS28 disease activity score 28, DMARDs disease-modifying antirheumatic drugs, ESR erythrocyte sedimentation rate, HAQ-DI Health Assessment Questionnaire-Disability Index, OR odds ratio, RF rheumatoid factor
  2. aDisease duration was divided into two groups based on a cut-off of 2 years
  3. bDAS28-ESR was divided into two groups, remission to low disease activity (DAS28-ESR ≤ 3.2) and moderate to high disease activity (DAS28-ESR > 3.2)