Which patient-specific and surgical characteristics influence postoperative pain after THA in a fast-track setting?

Table 1 The standardized multimodal protocol for perioperative pain medication

Timing	Medication
2 h before surgery	Paracetamol (acetaminophen) 1000 mg per os.
	Celecoxib (Celebrex®) ^a 400 mg per os.
	Gabapentin 600 mg per os.
Just before surgery	Dexamethasone 0.15 mg/kg iv. ^b
Just before surgery	Esketamine 15 mg iv.
4 h after surgery	Paracetamol (acetaminophen) 1000 mg per os.
8 h after surgery	Paracetamol (acetaminophen) 1000 mg per os.
8 h after surgery	Gabapentin 300 mg per os.
Before the night	Tramadol 100 mg supp.
Day 1	Paracetamol (acetaminophen) 1000 mg per os 4 times a day.
	Celecoxib (Celebrex®^{) a} 200 mg per os in the morning.
	Gabapentin 300 mg per os in the morning.
After day 1	Paracetamol (acetaminophen) 1000 mg per os 4 times a day (with a maximum of 2 weeks).
After day 1	Celecoxib (Celebrex®) ^a 200 mg per os in the morning (until 2 weeks after surgery).
Rescue medication	Celecoxib (Celebrex®) ^a 200 mg per os extra after the first night Piritramid (Dipidolor®) 10 mg im, which could be repeated every 4 h.

The standardized multimodal protocol for perioperative pain medication was determined based on literature [7,8,9,10,11,12]
^aIn combination with celecoxib (Celebrex®) all patients will receive omeprazol 20 mg per os once a day as prophylaxis. When the patient was already using a proton pomp inhibitor before admittance no omeprazol was administered
^bDexamethasone solution in 50cm³ saline is administered slowly to avoid adverse side effects like severe perianal pain

ISSN: 1471-2474