Latent class analysis derived subgroups of low back pain patients – do they have prognostic capacity?

Molgaard Nielsen, Anne; Hestbaek, Lise; Vach, Werner; Kent, Peter; Kongsted, Alice

doi:10.1186/s12891-017-1708-9

BMC Musculoskeletal Disorders

Table 3 Prognostic capacity for absolute outcomes

From: Latent class analysis derived subgroups of low back pain patients – do they have prognostic capacity?

			Follow-up time points
Outcome measure	Description of prognostic variable	Prognostic variable	2 weeks	3 months	12 months
Outcome measure	Description of prognostic variable	Prognostic variable	Adj. R²	Adj. R²	Adj. R²
Pain intensity (Numeric Rating Scale, 0–10)	LCA-derived subgroupings	Single-stage subgroups	0.069**	0.043**	0.063**
	LCA-derived subgroupings	Two-stage subgroups	0.065**	0.052**	0.047**
	Existing subgrouping tools	STarT Back Tool	0.037**	0.012*	0.017*
	Existing subgrouping tools	Quebec Task Force classification	0.018*	0.016*	0.008
	Baseline characteristics	Baseline back pain intensity (0–10 Numeric Rating Scale)	0.030**	0.007*	0.007*
		Baseline leg pain intensity (0–10 Numeric Rating Scale)	0.062**	0.016**	0.043**
		Baseline disability (RMDQ-23) (0–100 = highest disability)	0.024**	−0.001	0.004*
		Recovery belief (0–10 = very likely)	0.065**	0.109**	0.065**
	Results of first stage of two-stage LCA	All domain-specific patient categorisations	0.099**	0.126**	0.136**
Disability (23-item Roland Morris Disability Questionnaire, proportional score)	LCA-derived subgroupings	Single-stage subgroups	0.203**	0.113**	0.084**
	LCA-derived subgroupings	Two-stage subgroups	0.185**	0.113**	0.068**
	Existing subgrouping tools	STarT Back Tool	0.119**	0.079**	0.042**
	Existing subgrouping tools	Quebec Task Force classification	0.042**	0.052**	0.042**
	Baseline characteristics	Baseline back pain intensity (0–10 Numeric Rating Scale)	0.056**	0.011*	0.005*
		Baseline leg pain intensity (0–10 Numeric Rating Scale)	0.062**	0.053**	0.057**
		Baseline disability (RMDQ-23) (0–100 = highest disability)	0.193**	0.060**	0.045**
		Recovery belief (0–10 = very likely)	0.030**	0.107**	0.110**
	Results of first stage of two-stage LCA	All domain-specific patient categorisations	0.259**	0.199**	0.186**

Adj. adjusted, LCA Latent Class Analysis
*P < .05
**P < .001

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ISSN: 1471-2474

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