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Table 2 Genes the expression levels of which differed between untreated patients and untreated controls (78 genes)

From: Gene expression profiling in patients with polymyalgia rheumatica before and after symptom-abolishing glucocorticoid treatment

Gene symbol Gene name Probe set(s) FDa p
BDNF brain-derived neurotrophic factor 244503_at +1.8 0.016
ETS2 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) 201328_at +1.8 0.007
SVIP small VCP/p97-interacting protein 230285_at +1.7 0.002
SH3RF2 SH3 domain containing ring finger 2 228892_at +1.6 0.004
TM4SF18 transmembrane 4 L six family member 18 230061_at +1.5 0.007
TMTC1 transmembrane and tetratricopeptide repeat containing 1 226322_at 226931_at +1.5 +1.6 0.003 <0.001
TMEM18 transmembrane protein 18 225489_at +1.5 0.008
N4BP2L1 NEDD4 binding protein 2-like 1 213375_s_at +1.5 0.019
FMO2 flavin containing monooxygenase 2 (non-functional) 228268_at +1.5 0.002
RPL37 ribosomal protein L37 224763_at +1.5 <0.001
CTDSP2 CTD (carboxy-terminal domain. RNA polymerase II. polypeptide A) small phosphatase 2 238999_at +1.4 0.048
RASL10B RAS-like. Family 10. member B 235488_at +1.4 0.012
SMG1P1 nuclear pore complex interacting protein-like 231989_s_at +1.4 0.008
ZNF331 zinc finger protein 331 219228_at +1.4 <0.001
FAM184B family with sequence similarity 184. member B 235288_at +1.4 0.013
LOC100507303 uncharacterized LOC100507303 228049_x_at +1.4 0.019
NCKIPSD NCK interacting protein with SH3 domain 218697_at +1.4 <0.001
ECHDC3 enoyl CoA hydratase domain containing 3 219298_at +1.3 0.049
RNF114 ring finger protein 114 200867_at 200868_s_at 211678_s_at +1.3 +1.3 +1.2 0.006 0.023 0.018
TMPO thymopoietin 224944_at +1.3 0.002
RERE arginine-glutamic acid dipeptide (RE) repeats 200940_s_at +1.3 0.003
TUBD1 tubulin. Delta 1 231853_at +1.3 0.003
MARK4 MAP/microtubule affinity-regulating kinase 4 55065_at +1.3 0.005
ZNF195 zinc finger protein 195 204234_s_at +1.3 0.003
PCF11 PCF11. cleavage and polyadenylation factor subunit. Homolog (S. cerevisiae) 203378_at +1.3 0.007
DFFA DNA fragmentation factor. 45 kDa. alpha polypeptide 226116_at +1.3 0.010
PSPC1 paraspeckle component 1 218371_s_at +1.3 0.007
RBBP6 retinoblastoma binding protein 6 212783_at +1.3 0.004
EIF4B eukaryotic translation initiation factor 4B 211937_at +1.3 0.017
NPM1 nucleophosmin (nucleolar phosphoprotein B23. numatrin) 221691_x_at +1.3 0.011
RSBN1 round spermatid basic protein 1 213694_at +1.2 0.003
PSIP1 PC4 and SFRS1 interacting protein 1 209337_at +1.2 0.010
EIF3G eukaryotic translation initiation factor 3. subunit G 208887_at +1.2 0.006
COL4A3BP collagen. Type IV. alpha 3 (Goodpasture antigen) binding protein 219625_s_at 223465_at +1.2 +1.2 0.003 0.029
PCID2 PCI domain containing 2 219940_s_at +1.2 0.003
PXDC1 PX domain containing 1 212923_s_at +1.2 0.042
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 202331_at +1.2 0.024
AKR7A2 aldo-keto reductase family 7, member A2 202139_at +1.2 0.010
MRPS2 mitochondrial ribosomal protein S2 218001_at +1.2 0.018
RORA RAR-related orphan receptor A 226682_at +1.2 0.049
RPL36AL ribosomal protein L36a-like 207585_s_at +1.2 0.011
TFRC transferrin receptor (p90, CD71) 208691_at –3.0 0.004
SFRP4 secreted frizzled-related protein 4 204051_s_at 204052_s_at −2.9 0.001 0.002
NOV nephroblastoma overexpressed 214321_at −2.0 0.037
PAQR9 progestin and adipoQ receptor family member IX 1558322_a_at −2.0 <0.001
C2orf88 chromosome 2 open reading frame 88 228195_at −1.9 0.011
FAM69A family with sequence similarity 69, member A 213689_x_at −1.8 0.001
TP53INP2 tumor protein p53 inducible nuclear protein 2 224836_at −1.8 −1.9 <0.001 0.002
SH3KBP1 SH3-domain kinase binding protein 1 1554168_a_at 223082_at −1.8 0.002
NINJ2 ninjurin 2 219594_at −1.7 0.039
MEST mesoderm specific transcript homolog (mouse) 202016_at −1.7 0.010
ITGB1BP2 integrin beta 1 binding protein (melusin) 2 219829_at −1.6 <0.001
PLXDC1 plexin domain containing 1 219700_at −1.5 0.006
BPGM 2,3-bisphosphoglycerate mutase 203502_at −1.5 <0.001
MTFP1 mitochondrial fission process 1 223172_s_at −1.5 0.004
MAP2K3 mitogen-activated protein kinase kinase 3 215499_at −1.5 0.003
LRRN4CL LRRN4 C-terminal like 1556427_s_at −1.4 0.042
FBXO9 F-box protein 9 210638_s_at212987_at −1.4 −1.4 <0.001 <0.001
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 218306_s_at −1.4 <0.001
JARID2 jumonji, AT rich interactive domain 2 203297_s_at −1.4 <0.001
TRAK1 trafficking protein, kinesin binding 1 202079_s_at −1.4 0.004
ZNF252P zinc finger protein 252, pseudogene 228200_at −1.4 <0.001
PRSS23 protease, serine, 23 202458_at −1.4 0.030
OLFML2B olfactomedin-like 2B 213125_at −1.4 0.049
MSANTD4 Myb/SANT-like DNA-binding domain containing 4 with coiled-coils 227418_at −1.3 0.043
ZDHHC7 zinc finger, DHHC-type containing 7 218606_at −1.3 <0.001
RAP2A RAP2A, member of RAS oncogene family 225585_at −1.3 0.016
LRP12 low density lipoprotein receptor-related protein 12 219631_at −1.3 0.050
BMPR1A bone morphogenetic protein receptor, type IA 213578_at −1.3 0.001
RNF10 ring finger protein 10 207801_s_at −1.3 <0.001
COL5A1 collagen, type V, alpha 1 203325_s_at −1.3 0.007
INSIG1 insulin induced gene 1 201626_at −1.3 0.046
SLC35E3 solute carrier family 35, member E3 218988_at −1.3 0.003
MEMO1 dpy-30 homolog (C. elegans) /// mediator of cell motility 1 219065_s_at −1.3 0.004
MYL4 myosin, light chain 4, alkali; atrial, embryonic 210395_x_at −1.2 0.002
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 201597_at −1.2 0.019
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B 224598_at −1.2 0.003
MRC2 mannose receptor, C type 2 209280_at −1.2 0.010
  1. FD fold difference. a fold differences for genes with more than one probe set were calculated as the average of the individual values, which did not differ markedly