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Table 1 Patients’ data overview

From: Long-term outcome following additional rhBMP-7 application in revision surgery of aseptic humeral, femoral, and tibial shaft nonunion

  Humerus Femur Tibia
with rhBMP-7 without rhBMP-7 with rhBMP-7 without rhBMP-7 with rhBMP-7 without rhBMP-7
Group size 13 9 28 13 21 28
Gender: Male / female 7 / 6 6 / 3 17 / 11 11 / 2 14 / 7 20 / 8
Age [years] 49.0 ± 4,7 51.0 ± 4.2 55.2 ± 2.6 42.4 ± 3.8 51.6 ± 2.7 42.3 ± 2.6
Closed / open fracture 11 / 2 7 / 2 24 / 4 10 / 3 14 / 7 18 / 10
Nicotine abuse 6 2 4 1 10 6
Diabetes mellitus 2 0 2 1 4 0
Steroid therapy 0 0 1 0 0 0
Charlson comorbidity index [33] 0.23 ± 0.12 0.33 ± 0.17 0.41 ± 0.15 0.31 ± 0.17 0.38 ± 0.16 0.14 ± 0.08
Period of time between index operation and revision surgery [months] 14.8 ± 3.8 11.7 ± 1.1 10.3 ± 2.6
  1. Results are presented as mean ± standard error of the mean (SEM) or median
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