Skip to main content

Table 3 Independent associations with the health-related quality of life measures SF-36, SF-6D and 15D explored in 380 patients with axial spondyloarthritis in outpatient clinics

From: The relationship between demographic- and disease-related variables and health-related quality of life in patients with axial spondyloarthritis

  SF-36-PCS
Range 0–100
  SF-36-MCS
Range 0–100
  15D
Range 0–1
  SF-6D
Range 0–1
 
  Adj. B (95% CI) p Adj. B (95% CI) p Adj. B (95% CI) p Adj. B (95% CI) p
Demographic factors
 Age (years) −0.01 (−0.08, 0.06) 0.799 0.75 (−0.03, 0.18) 0.161 0.000 (0.000, 0.001) 0.267 0.000 (0.000, 0.001) 0.306
 Female 0.19 (−1.54, 1.92) 0.830 0.27 (−2.23, 2.77) 0.834 −0.011 (−0.027, 0.005) 0.192 0.004 (−0.015, 0.023) 0.693
 Living alone 0.40 (−1.45, 2.26) 0.669 −0.49 (−3.78, 2.19) 0.718 0.002 (−0.016, 0.019) 0.838 −0.005 (−0.025, 0.016) 0.644
 Employment −1.15 (−3.05, 0.74) 0.233 −2.46 (−5.20, −0.29) 0.079 −0.014 (−0.031, 0.004) 0.135 −0.015 (−0.036, 0.006) 0.164
Education duration
 ≤ 10 years −0.86 (−3.41, −1.69) 0.506 −0.71 (−4.41, −2.97) 0.666 −0.019 (−0.042, 0.005) 0.119 0.018 (−0.010, 0.047) 0.207
 11–13 years −0.01 (−1.68, 1.70) 0.992 0.09 (−2.35, 2.54) 0.701 0.007 (−0.009, 0.023) 0.392 −0.001 (−0.020, 0.017) 0.893
 > 13 years Ref   Ref   Ref   Ref  
 Exercise >3 h per week 2.71 (0.21, 4.99) 0.020 2.58 (−0.72, 5.89) 0.125 0.036 (0.015, 0.058) 0.001 0.053 (0.028, 0.078) <0.001
 Exercise 1–3 h per week 2.73 (0.40, 5.06) 0.022 1.84 (−1.54, 5.21) 0.284 0.032 (0.010, 0.53) 0.004 0.045 (0.019, 0.070) 0.001
 Exercise <1 h per week Ref   Ref   Ref   Ref  
 Current smoker −1.07 (−2.81, 0.67) 0.227 −1.40 (−1.12, 3.91) 0.275 0.009 (−0.007. 0.025) 0.284 −0.002 (−0.021, 0.017) 0.842
Alcohol (per week)
 Never −0.70 (−3.82, −2.23) 0.607 2.74 (−1.62, 7.02) 0.217 0.004 (−0.025, 0.032) 0.798 0.010 (−0.023, 0.043) 0.556
 1–6 glasses −0.85 (−3.49, −1.80) 0.530 4.63 (0.80, 8.46) 0.018 0.010 (−0.015, 0.034) 0.428 0.019 (−0.010. 0.048) 0.198
 7 or more glasses Ref.   Ref.   Ref.   Ref.  
 BMI (kg/m2) 0.23 (−0.16, 0.20) 0.799 0.03 (−0.23, −0.28) 0.827 −0.001 (−0.002, 0.001) 0.447 0.001 (−0.002, 0.002) 0.884
Disease activity
Measures
 BASDAI (range 0–10) −0.21 (−0.81, 0.57) 0.729 −0.38 (−1.37, 0.62) 0.459 −0.004 (−0.011, 0.002) 0.201 0.002 (−0.006, 0.010) 0.659
 MASES (range 0–13) −0.09 (−0.32, 0.13) 0.421 −0.02 (−0.35, 0.31) 0.911 −0.001 (−0.003, 0.001) 0.251 0.001 (−0.003, 0.002) 0.885
Health status
 BASFI (range 0–10) −1.05 (−1.86, −0.25) 0.010 1.02 (−0.15, 2.18) 0.086 −0.004 (−0.011, 0.004) 0.348 0.001 (−0.008, 0.010) 0.866
 BAS-G (range 0–10) −0.91 (−1.45, −0.37) 0.001 −1.73 (−2.51, −0.95) <0.001 −0.010 (−0.015, −0.005) <0.001 −0.020 (−0.026, −0.014) <0.001
 HAQ (range 0–3) −4.61 (−7.30, −1.91) 0.001 −2.00 (−5.91, 1.90) 0.313 −0.051 (−0.076, −0.026) <0.001 −0.054 (−0.084, −0.024) 0.001
Damage score
 BASMI (range 0–10) −0.11 (−0.56, 0.34) 0.629 0.05 (−0.60, 0.69) 0.883 0.001 (−0.003, 0.005) 0.730 −0.002 (−0.007, 0.003) 0.488
Co-morbidity
 Mean total score for co-morbidity (range 0–10) −0.19 (−1.20, 0.82) 0.715 −0.64 (−2.10, 0.82) 0.388 −0.014 (−0.023, −0.005) 0.004 −0.002 (−0.014,0.009) 0.661
Centre
 SSHF (N/Y) −1.58 (−3.34, 0.18) 0.079 1.47 (−1.08, 4.02) 0.256 −0.005 (−0.021, −0.012) 0.582 −0.013 (−0.032, 0.007) 0.199
R2 57.1%   21.5%   60.2%   56.9%  
  1. Adjusted analyses were performed using multiple regression analyses and applying a general linear model using SPSS. Bold p values indicate significant differences
  2. Key: Adj adjusted unstandardized regression coefficients with 95% confidence interval (CI) and p-values; SF-36-PCS, physical component summary scale; SF-36-MCS, mental component summary scale, BMI body mass index, BASDAI Bath Ankylosing Spondylitis Disease Activity Index, MASES Maastricht Ankylosing Spondylitis Enthesitis Score, BASFI Bath Ankylosing Spondylitis Functional Index, BAS-G Bath Ankylosing Spondylitis Patient Global Score, HAQ Health Assessment Questionnaire, BASMI Bath Ankylosing Spondylitis Metric Index, Ref reference values for statistical comparison