From: HLA B27 antigen in Middle Eastern and Arab countries: systematic review of the strength of association with axial spondyloarthritis and methodological gaps
Quality Indicator
Number of studies / Total studies
Sample size
 - AS <30 patients
8 / 22
 - AS >50 patients
12 / 22
Presence of control group
11 / 27
Method of HLA-B27 testing stated
3 / 27
Homogeneous and clear inclusion criteria
14 / 22