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Table 4 Oxidative stress and antioxidative capacity measurements from blood samples

From: Effect of vitamin E on oxidative stress level in blood, synovial fluid, and synovial tissue in severe knee osteoarthritis: a randomized controlled study

  Group A (placebo) Group B (vitamin E) p value
Oxidative agents and products
- Nitrite (μM)
 Pre-intervention 5.55 ± 0.57 5.60 ± 1.09 0.96
 Post-intervention 5.63 ± 0.58 3.89 ± 1.25 0.19
 ∆ (post − pre) 0.08 ± 0.03 −1.70 ± 1.2 0.12
- Malondialdehyde (μM)
 Pre-intervention 1.32 ± 0.11 1.43 ± 0.07 0.43
 Post-intervention 1.34 ± 0.10 1.00 ± 0.09 0.02a
 ∆ (post − pre) 0.01 ± 0.02 −0.79 ± 0.39 0.03a
Antioxidative agents
- Alpha-tocophorol (μg/ml)
 Pre-intervention 15.50 ± 0.98 16.24 ± 0.99 0.59
 Post-intervention 15.92 ± 1.08 24.65 ± 1.47 <0.01a
 ∆ (post − pre) 0.43 ± 0.33 8.41 ± 1.18 <0.01a
- FRAP (mM)
 Pre-intervention 923.30 ± 29.46 905.20 ± 35.16 0.69
 Post-intervention 951.30 ± 29.03 1020 ± 40.22 0.17
 ∆ (post − pre) 28.01 ± 9.11 114.4 ± 35.19 0.01a
- TEAC (mM)
 Pre-intervention 4.26 ± 0.10 4.56 ± 0.14 0.08
 Post-intervention 4.22 ± 0.10 5.04 ± 0.10 <0.01a
 ∆ (post − pre) −0.04 ± 0.05 0.89 ± 0.45 0.03a
  1. Data are presented as mean ± standard deviation
  2. P value represent the test between groups
  3. FRAP ferric reducing antioxidant power, TEAC Trolox equivalent antioxidant capacity
  4. aStatistically significant