|
Algorithms
|
Sensitivity %, (95% CI)
|
Specificity %, (95% CI)
|
PPV %, (95% CI)
|
LR+ (95% CI)
|
|---|
|
A: ≥1 ICD-9 code for AVN
|
81.9 (72.0–89.5)
|
99.6 (99.4–99.7)
|
66.0 (56.0–75.1)
|
190.0 (134.5–268.5)
|
|
B: ≥2 ICD-9 codes for AVN at least 7 days apart
|
57.8 (46.5–68.6)
|
99.9 (99.8–99.9)
|
81.4 (69.1–90.3)
|
426.7 (229.9–792.1)
|
|
C: ≥2 ICD-9 codes for AVN at least 30 days apart
|
44.6 (33.7–55.9)
|
99.9 (99.8–99.9)
|
78.7 (64.3–89.3)
|
361.8 (186.2–703.1)
|
|
D: ≥3 ICD-9 codes for AVN at least 30 days apart
|
44.6 (33.7–55.9)
|
99.9 (99.8–100.0)
|
82.2 (67.9–92.0)
|
452.3 (217.3–941.4)
|
- All ICD-9 codes occurred within 6 months of MRI.
- Abbreviations: ICD-9 International Classification of Diseases, 9th version, CI Confidence Interval; PPV Positive Predictive Value, LR
+ Positive Likelihood Ratio
- The sensitivity of algorithm C is actually 44.578 and specificity of 99.877, whereas the sensitivity of algorithm D is 44.578 and the specificity is 99.901, accounting for the discrepancy in the observed likelihood ratios of algorithm C and D.
