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Table 1 Univariate analysis for risk factors associated with reinfection of two-stage revision THAData are mean (range) or number (%) of episodes

From: The risk factors of failed reimplantation arthroplasty for periprosthetic hip infection

  Variable Success (N = 51) Reinfection (N = 11) HR (95% CI) p value
  Age (years) 57.8 (27–86) 53.2 (42–79) 0.97 (0.93–1.02) 0.3621
  Male 36 (70%) 7 (63%) 1.44 (0.42–4.93) 0.5587
Patient characteristics BMI (kg/m2)
 <30 43 (84%) 5 (46%)  
 ≥30 8 (16%) 6 (54%) 4.92 (1.50–16.1) 0.0085*
Smoking 17 (33%) 5 (45%) 1.55 (0.47–5.11) 0.4641
ASA
 2 28 (55%) 3 (27%)  
 3 23 (45%) 8 (73%) 2.97 (0.78–11.2) 0.1077
Diabetes mellitus 8 (16%) 2 (18%) 1.24 (0.26–5.78) 0.7764
Hepatitis 10 (20%) 4 (36%) 2.16 (0.63–7.40) 0.2176
Medical diseases Gout 6 (12%) 3 (27%) 2.27 (0.60–8.57) 0.2257
CKD 5 (10%) 1 (9%) 1.00 (0.12–7.86) 0.9987
ESRD 1 (2%) 1 (9%) 3.96 (0.50–31.2) 0.1910
Drug abuse 0 (0%) 2 (18%) 10.1 (2.11–48.0) 0.0037*
Liver cirrhosis 4 (9%) 6 (54%) 7.94 (2.39–26.2) 0.0007*
Autoimmune disease 3 (6%) 1 (9%) 1.81 (0.22–14.4) 0.5579
Staphylococcus aureus 7 (13.7%) 2 (18.1%) 1.43 (0.31–6.67) 0.6425
Coagulase-negative Staphylococcus 1 (1.9%) 1 (9%) 3.46 (0.43–27.7) 0.2413
Microbiology Methicillin-resistant organism 10 (19.6%) 1 (9%) 0.43 (0.05–3.40) 0.4287
Gram-negative organism 4 (9%) 4 (36.3) 4.83 (1.40–16.6) 0.0124*
Polymicrobial organism 4 (9%) 1 (9%) 1.57 (0.20–12.3) 0.6651
Culture-negative 16 (31.3%) 2 (18.1%) 0.49 (0.10–2.28) 0.3671
Presence of sinus tract 6 (12%) 7 (63%) 9.24 (2.66–32.0) 0.0005*
Interim period less than 3 months 9 (17%) 3 (27%) 1.78 (0.47–6.74) 0.3949
Operation-related factors Repeated debridement between stage 18 (35%) 10 (91%) 13.7 (1.75–107) 0.0125*
Perioperative Blood loss >1500 ml 18 (35%) 5 (45%) 1.37 (0.41–4.49) 0.6031
Revision operative time >4 h 26 (51%) 10 (91%) 8.47 (1.08–66.3) 0.0419*
Allograft use in revision 42 (82%) 9 (82%) 1.04 (0.22–4.83) 0.9586
  1. BMI body mass index, ASA American Society of Anesthesiologist, ESRD end stage renal disease, CKD chronic kidney disease, HR hazard ratio, CI confidence interval
  2. *A p value of <0.05 was considered to be statistically significant