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Fig. 4 | BMC Musculoskeletal Disorders

Fig. 4

From: The mitochondrial inhibitor oligomycin induces an inflammatory response in the rat knee joint

Fig. 4

Oligomycin modulates COX-IV levels in the synovial tissue. a Immunofluorescence microscopy analysis of synovial tissue sections from OLI-vehicle or OLI injected joints stained for COX-IV (red) with DAPI counterstaining (blue). Representative images are presented. b Fluorescence levels were measured and calculated as described in Methods. Values, expressed in arbitrary units (AU), represent mean ± SEM (n = 7 independent synovial sections). *P ≤ 0.05 vs OLI-vehicle knees. OLI, oligomycin; DAPI, 4′,6-diamidino-2-phenylindole; COX-IV, cytochrome c oxidase subunit IV

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