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Table 3 Summary of the collected data displaying distribution of the parameters investigated in the group with implant survival/preservation and the group in whom the implant was removed

From: Factors influencing treatment success of negative pressure wound therapy in patients with postoperative infections after Osteosynthetic fracture fixation

Variable Description Survival of the implant until bony consolidationa p-valueb
Yes No
n Mean or % SD n Mean or % SD
Gender Male 38 80.9   37 64.9   0.0712
Female 9 19.1   20 35.1   
Age   47 55.5 18.5 57 52.1 18.9 0.3006
Stay at ICU days 47 4.5 6.5 57 3.1 5.5 0.4337
Initial procedure Open 45 95.7   1 1.8   0.5881
  Closed 2 4.3   56 98.2   
Tissue damage Open Grade 0-2 7 14.9   11 19.3   0.042
Open Grade 3-4 2 4.3   11 19.3   
Closed 38 80.9   35 61.4   
Identification of a Yes 43 91.5   48 84.2   0.2640
microbial strain No 4 8.5   9 15.8   
Presence of a bacterial mixture Yes 5 10.6   15 26.3   0.0413
No 38 80.8   33 57.9   
No detectable germ 4 8.5   9 15.8   
Change in microbial strain during treatment Yes 40 85.1   40 70.2   0.0721
No 7 14.9   17 29.8   
Gram Stain Positive 34 72.3   39 68.4   0.8615
Negative 8 17.0   10 17.5   
None 5 10.6   8 14.0   
Bacterial metabolism Aerobic 3 6.4   4 7.0   0.2172
Anaerobic 1 2.1   2 3.5   
Facultative anaerobic 38 80.9   37 64.9   
Facultative aerobic 0 0.0   5 8.8   
No detectable germ 5 10.6   9 15.8   
Bacterial load Plentiful 10 21.3   17 29.8   0.7030
Numerous 17 36.2   15 26.3   
Sporadic 13 27.7   14 24.6   
Enrichment 2 4.3   2 3.5   
No detectable germ 5 10.6   9 15.8   
Number of lavages until eradication sponge changes 0 23 48.9   27 47.4   0.6821
sponge changes 1 13 27.7   13 22.8   
sponge changes 2 4 8.5   9 15.8   
sponge changes ≥3 times 7 14.9   4 7.0   
Never be eradicated 0 0.0   4 7.0  
CRP Initial [mg/l] 45 81.5 94.1 50 72.6 85.1 0.7201
CRP Maximum [mg/l] 47 147.6 102.6 52 115.2 95.2 0.2187
CRP Discharge [mg/l] 46 23.2 39.2 53 24.9 32.9 0.6668
CRP Discharge ≤20 mg/l 34 73.9   35 66.0   0.5113
>20 mg/l 12 26.1   18 34.0   
Time Point of Infection Early 36 76.6   27 48.2   0.0032
Late 11 23.4   29 51.8   
Extent of Infection Superficial 0 0.0   2 3.5   0.4998
Deep 47 100.0   55 96.5   
Metabolic diseasec Yes 8 17.0   9 15.8   0.8657
No 39 82.0   48 84.2   
Re-infection Yes 14 29.8   23 40.4   0.3951
No 33 70.2   34 59.6   
Curing the Infection Yes 40 85.1   35 61.4   0.0086
No 7 14.9   22 38.6   
  1. SD = standard deviation, an total = 106, missing data on implant survival until bony consolidation n = 2, b in all analysis two-tailed tests with a significance level of 0.05 were used, c metabolic diseases = kidney diseases, liver diseases and diabetes mellitus