|
PDQ
|
NRSR
|
NRSW
|
---|
T0
|
T1
|
T2
|
T3
|
T4
|
T0
|
T1
|
T2
|
T3
|
T4
|
---|
PGE2
|
0.43, 0.001*
|
0.08, 0.588
|
0.38, 0.004
|
0.36, 0.007
|
0.03, 0.806
|
0.15, 0.286
|
0.52, <0.001*
|
0.33, 0.017
|
0.29, 0.032
|
0.26, 0.055
|
0.14, 0.317
|
IL-6
|
0.34, 0.011
|
0.08, 0.577
|
0.17, 0.225
|
0.09, 0.542
|
−0.22, 0.115
|
−0.12, 0.409
|
0.47, <0.001*
|
0.31, 0.021
|
0.27, 0.051
|
0.25, 0.065
|
0.07, 0.625
|
IL-8
|
0.15, 0.264
|
0.32, 0.019
|
0.10, 0.464
|
0.04, 0.763
|
−0.16, 0.254
|
−0.21, 0.122
|
0.74, <0.001*
|
0.16, 0.235
|
0.22, 0.109
|
0.20, 0.157
|
0.13, 0.350
|
TNF-α
|
0.28, 0.043
|
0.30, 0.029
|
0.19, 0.159
|
0.30, 0.028
|
−0.05, 0.740
|
−0.15, 0.295
|
0.76, <0.001*
|
0.25, 0.069
|
0.22, 0.116
|
0.22, 0.111
|
0.26, 0.062
|
-
Abbreviations: NRSR numerical rating scale at rest, NRSW numerical rating scale at walking, PDQ pain disability questionnaire, PGE2 prostaglandin E2, IL interleukin, TNF-α tumor necrosis factor alpha, T0 24 h before surgery, T1-T4 24, 48, 72 h and 5 days after surgery, respectively. The p-values are presented in their raw, uncorrected form, but the statistical significance for multiple comparisons were further corrected using the conservative Bonferroni p value (0.05/15 = 0.003) to control the family-wise error rate, and p < 0.003 are deemed significant (*)