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Table 5 Number of patients experiencing common adverse Events (>1% of Population)

From: Efficacy and safety of single injection of cross-linked sodium hyaluronate vs. three injections of high molecular weight sodium hyaluronate for osteoarthritis of the knee: a double-blind, randomized, multi-center, non-inferiority study

Preferred Term

HMWHA

XLHA

N = 146 (%)

N = 139 (%)

Diarrhoea

3 (2.1)

1 (0.7)

Dyspepsia

1 (0.7)

2 (1.4)

Injection site pruritus

2 (1.4)

1 (0.7)

Pain

1 (0.7)

4 (2.9)

Pyrexia

0 (0)

3 (2.2)

Cystitis

2 (1.4)

2 (1.4)

Nasopharyngitis

3 (2.1)

7 (5)

Upper respiratory tract infection

0 (0)

3 (2.2)

Joint swelling

0 (0)

2 (1.4)

Musculoskeletal pain

0 (0)

2 (1.4)

Pain in extremity

6 (4.1)

3 (2.2)

Plantar fasciitis

0 (0)

2 (1.4)

Headache

5 (3.4)

1 (0.7)

Paraesthesia

0 (0)

2 (1.4)

Cough

3 (2.1)

0 (0)

Erythema

0 (0)

2 (1.4)