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Table 3 Responder rate (Per-protocol Set)

From: Efficacy and safety of single injection of cross-linked sodium hyaluronate vs. three injections of high molecular weight sodium hyaluronate for osteoarthritis of the knee: a double-blind, randomized, multi-center, non-inferiority study

  HMWHA XLHA P-valueA
N = 111 (%) N = 97 (%)
Decrease in weight-bearing pain ≥ 20 mm or ≥ 40% improvement  
 Visit 5 52 (46.85) 46 (47.42) 0.93
 Visit 6 66 (59.46) 70 (72.16) 0.05
 Visit 7 76 (68.47) 73 (75.26) 0.28
OMERACT-OARSI response
 Visit 5 38 (34.23) 28 (28.87) 0.41
 Visit 6 48 (43.24) 47 (48.45) 0.45
 Visit 7 55 (49.55) 57 (58.76) 0.18
  1. A, P-value obtained from Chi-square test