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Table 1 Characteristic of Rheumatoid Arthritis patients and Healthy Controls

From: Association between antibodies to carbamylated proteins and subclinical atherosclerosis in rheumatoid arthritis patients

 

RA (n = 50)

NHS (n = 30)

P

Demographics

 Age (mean ± SD, yrs)

58.4 + 13.1

56.7 + 16.7

ns

 Sex (n, % female)

34 (68.0)

20 (66.6)

ns

Inflammatory markers

 ESR (mm/h, mean ± IQR)

22.9 + 17.6

10.6 + 9.3

0.000

 CRP (mg/L ± IQR)

5.4 + 5.7

2.9 + 1.7

0.000

RA disease characteristics

 Disease duration (months, mean ± SD)

127 + 97.6

n.a.

n.a.

 DAS 28 (mean ± SD)

4.0 + 1.5

n.a.

n.a.

 ACPA positivity (n, %)

35 (70)

0 (0)

0.000

 RF positivity (n, %)

34 (68)

0 (0)

0.000

 Anti-CarP positivity (n, %)

19 (38)

0 (0)

0.000

Traditional Cardiovascular risk factors

 Smoking, current (n, %)

15 (30)

5 (16.6)

0.002

 Systolic blood pressure (mmHg, mean ± SD)

135.5 + 19.5

135.06 + 19.01

ns

 Diastolic blood pressure (mmHg, mean ± SD)

84.5 + 10.8

80.5 + 8.91

ns

 Total Cholesterol (mg/dl, mean ± SD)

188 + 37.6

186 + 34.6

ns

 HDL cholesterol (mg/dl, mean ± SD)

60.06 + 14.25

40.5 + 6.6

0.001

 LDL cholesterol (mg/dl, mean ± SD)

117 + 35.5

114 + 32.3

0.02

 Triglycerides (mg/dl, mean ± SD)

93.2 + 35.9

93.1 + 35.01

ns

 Body Mass Index (kg/m2, mean ± SD)

24.8 + 4.19

25.4 + 4.54

ns

  1. ESR erythrosedimentation rate, CRP C reactive protein, DAS28 Disease Activity Score 28, ACPA anti-citrullinated peptides antibodies, RF Rheumatoid Factor, anti-CarP anti-carbamylated protein antibodies, HDL high density lipoproteins, LDL low density lipoproteins