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Table 1 Characteristic of Rheumatoid Arthritis patients and Healthy Controls

From: Association between antibodies to carbamylated proteins and subclinical atherosclerosis in rheumatoid arthritis patients

  RA (n = 50) NHS (n = 30) P
Demographics
 Age (mean ± SD, yrs) 58.4 + 13.1 56.7 + 16.7 ns
 Sex (n, % female) 34 (68.0) 20 (66.6) ns
Inflammatory markers
 ESR (mm/h, mean ± IQR) 22.9 + 17.6 10.6 + 9.3 0.000
 CRP (mg/L ± IQR) 5.4 + 5.7 2.9 + 1.7 0.000
RA disease characteristics
 Disease duration (months, mean ± SD) 127 + 97.6 n.a. n.a.
 DAS 28 (mean ± SD) 4.0 + 1.5 n.a. n.a.
 ACPA positivity (n, %) 35 (70) 0 (0) 0.000
 RF positivity (n, %) 34 (68) 0 (0) 0.000
 Anti-CarP positivity (n, %) 19 (38) 0 (0) 0.000
Traditional Cardiovascular risk factors
 Smoking, current (n, %) 15 (30) 5 (16.6) 0.002
 Systolic blood pressure (mmHg, mean ± SD) 135.5 + 19.5 135.06 + 19.01 ns
 Diastolic blood pressure (mmHg, mean ± SD) 84.5 + 10.8 80.5 + 8.91 ns
 Total Cholesterol (mg/dl, mean ± SD) 188 + 37.6 186 + 34.6 ns
 HDL cholesterol (mg/dl, mean ± SD) 60.06 + 14.25 40.5 + 6.6 0.001
 LDL cholesterol (mg/dl, mean ± SD) 117 + 35.5 114 + 32.3 0.02
 Triglycerides (mg/dl, mean ± SD) 93.2 + 35.9 93.1 + 35.01 ns
 Body Mass Index (kg/m2, mean ± SD) 24.8 + 4.19 25.4 + 4.54 ns
  1. ESR erythrosedimentation rate, CRP C reactive protein, DAS28 Disease Activity Score 28, ACPA anti-citrullinated peptides antibodies, RF Rheumatoid Factor, anti-CarP anti-carbamylated protein antibodies, HDL high density lipoproteins, LDL low density lipoproteins