Fig. 3
From: IL-10 ameliorates TNF-α induced meniscus degeneration in mature meniscal tissue in vitro
Glycosaminoglycan release in TNF-α stimulated meniscus explants was reduced by IL-10. GAG release was measured in supernatants of mature bovine meniscus explants under normal culture conditions (control), the influence of IL-10 [10 ng/ml], or after treatment with proinflammatory TNF-α (10 and 100 ng/ml). Figure a displays results of five independent experiments (n = 5) with IL-10 [10 ng/ml]. A concentration series for IL-10 is given in figure b (n = 3). a-c indicate clusters of experimental groups which are significantly different from each other with P < 0.05 (detailed p-values are given in the text). Data are presented as mean ± 95 CI