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Table 3 Data of erythrocyte sedimentation rate and Schirmer test results in the included studies

From: Is hydroxychloroquine effective in treating primary Sjogren’s syndrome: a systematic review and meta-analysis

Author Year Region Outcomes Hydroxychloroquine Placebo
N Mean difference sd N Mean difference sd
Yoon C.H et al. 2016 Korea ESR 11 -3.64 19.30 15 1.73 11.75
Schirmer test 11 -1.45 4.31 15 -0.80 2.89
Gottenberg J.E et al. 2014 France ESR 44 -4.0 22.3 48 3.7 15.5
Schirmer test 37 2.14 8.83 36 0.62 7.50
Kruize A.A et al. 1993 Netherlands ESR 8 -10.3 17.1 6 -0.9 25.5
Schirmer test 8 -1.6 9.4 6 0.3 7.6
  1. Abbreviations: ESR erythrocyte sedimentation rate