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Table 1 Demographic features for subjects whose disc tissue was evaluated with immunohistochemistry or whose tissue or cells were utilized for molecular analysis

From: Mucin 1, a signal transduction membrane-bound mucin, is present in human disc tissue and is downregulated in vitro by exposure to IL-1ß or TNF-α

Subject number Age Thompson score Vertebral level Specimen typea Experimental useb
1 34 I Lumbar CHTN Mol
2 30 II L3-4 CHTN Mol
3 30 II L3-4 CHTN Mol
4 54 II L4-5 Surgical specimen Mol
5 21 II L5-S1 Surgical specimen Mol
6 40 II L4-5 Surgical specimen Mol
7 41 V L4-5 Surgical specimen Mol
8 57 V C6-7 Surgical specimen Mol
9 72 V L4-S1 Surgical specimen Mol
10 1 I Lumbar CHTN Imm
11 Newborn I Lumbar CHTN Imm
12 21 II L5-S1 Surgical specimen Imm
13 24 II L5-S1 Surgical specimen Imm
14 41 II L5-S1 Surgical specimen Imm
15 29 III L5-S1 Surgical specimen Imm
16 53 III L5-S1 Surgical specimen Imm
17 54 III L4-5 Surgical specimen Imm
18 58 III L2-3 Surgical specimen Imm
19 39 IV L4-5 Surgical specimen Imm
20 56 IV L2-3 Surgical specimen Imm
21 59 IV L2-3 Surgical specimen Imm
22 78 IV L3-4 Surgical specimen Imm
23 39 V L5-S1 Surgical specimen Imm
24 56 V L5-S1 Surgical specimen Imm
25 62 V L5-S1 Surgical specimen Imm
26 59 IV L4-5 Surgical specimen 3D and Mol
27 59 IV L4-5 Surgical specimen 3D and Mol
28 57 III C4-5 Surgical specimen 3D and Mol
29 54 IV L3-4 Surgical specimen 3D and Mol
  1. a CHTN Cooperative Human Tissue Network, normal donor specimen, OR surgical specimen, L lumbar, C cervical
  2. b Imm immunohistochemistry on disc tissue, 3D and Mol cells cultured in 3D and 3D mRNA harvested for microarray analysis, Mol human annulus tissue mRNA harvested for microarray analysis