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Fig. 4 | BMC Musculoskeletal Disorders

Fig. 4

From: Mucin 1, a signal transduction membrane-bound mucin, is present in human disc tissue and is downregulated in vitro by exposure to IL-1ß or TNF-α

Fig. 4

Representative images of cells cultured in 3D with immunolocalization of MUC1. a. Cells in the 3D construct under control; b. IL-1ß-treated cells; c. TNF-α-treated cells. “3D” marks the collagen sponge framework in which cells were cultured. d.  Representative image from a negative control. (Arrows mark cells which do not show localization. Bar = 10 μm)

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