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Fig. 1 | BMC Musculoskeletal Disorders

Fig. 1

From: Mucin 1, a signal transduction membrane-bound mucin, is present in human disc tissue and is downregulated in vitro by exposure to IL-1ß or TNF-α

Fig. 1

Representative images showing immunolocalization of MUC1. a Grade IV specimen shows the outer annulus, with many spindle-shaped cells. b Large cluster of cells in the inner annulus showing cells with positive or negative localization. c Cytoplasmic immunolocalization present in an inner annulus cell from a grade IV specimen. d Localization along the rim of the lacunar margin of a disc cell in the inner annulus. e Fewer immunopositive cells were present in the nucleus pulposus regions of the disc. f Negative control section adjacent to that shown in a. (Arrows mark cells which do not show localization. Bar = 20 μm)

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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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