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Table 4 Subgroup analysis of changes in the JKOM and VAS scores in patients with coexisting PFOA according to PFOA location

From: Changes in clinical symptoms and functional disability in patients with coexisting patellofemoral and tibiofemoral osteoarthritis: a 1-year prospective cohort study

Variable

Isolated lateral (n = 18)

Isolated medial (n = 4)

Mixed (n = 23)

 

Two-way ANCOVAa

Baseline

1-year follow-up

Mean change

Baseline

1-year follow-up

Mean change

Baseline

1-year follow-up

Mean change

 

Timeb

Groupc

Interaction

Mean ± SD

Mean ± SD

Mean (95% CI)

Mean ± SD

Mean ± SD

Mean (95% CI)

Mean ± SD

Mean ± SD

Mean (95% CI)

 

Adjusted P-value

JKOM

 Pain and stiffness (0–32 points)

9.28 ± 6.17

7.39 ± 7.62

-1.89 (-4.31, 0.53)

12.5 ± 4.79

14.8 ± 9.11

2.50 (-2.40, 7.40)

12.2 ± 6.25

14.2 ± 7.64

2.00 (-2.71, 6.71)

d

0.654

0.012

0.426

 Activities of daily living (0–40 points)

9.06 ± 7.68

9.11 ± 9.56

0.06 (-3.96, 4.07)

11.5 ± 8.58

15.3 ± 12.7

3.75 (-2.04, 9.54)

12.8 ± 9.69

14.1 ± 7.60

1.14 (-4.88, 7.17)

 

0.438

0.057

0.823

 Participation in social activities (0–20 points)

5.06 ± 5.06

3.06 ± 4.40

-2.00 (-4.34, 0.34)

4.50 ± 2.65

6.75 ± 4.99

2.25 (-0.33, 4.83)

5.70 ± 4.69

4.91 ± 3.85

-0.78 (-5.88, 4.31)

 

0.883

0.531

0.444

 General health conditions (0–8 points)

2.61 ± 1.82

2.72 ± 1.84

0.11 (-0.97, 1.20)

2.50 ± 0.58

3.75 ± 0.96

1.25 (0.02, 2.48)

3.78 ± 1.86

3.74 ± 1.14

-0.04 (-1.53, 1.45)

d

0.321

0.016

0.566

 Total score (0–100 points)

25.2 ± 17.5

21.6 ± 21.3

-3.61 (-11.7, 4.47)

30.0 ± 14.8

39.3 ± 25.5

9.25 (-3.03, 21.5)

34.3 ± 17.6

36.0 ± 15.2

1.65 (-10.3, 13.6)

d

0.607

0.013

0.572

 VAS score for knee pain, mm

38.9 ± 30.1

28.2 ± 30.2

-10.8 (-21.5, -0.08)

24.5 ± 15.9

46.5 ± 34.6

22.0 (0.64, 43.3)

45.1 ± 26.0

54.3 ± 26.8

9.17 (-21.0, 39.3)

d

0.385

0.033

0.167

  1. PFOA Patellofemoral osteoarthritis, ANCOVA Analysis of covariance, 95% CI 95% confidence interval, JKOM Japanese Knee Osteoarthritis Measure, VAS Visual analog scale
  2. P-values indicating statistically significant differences (<0.05) are displayed in bold
  3. aAdjusted P-values were calculated from the ANCOVA adjusted for age, sex, and body mass index
  4. bBaseline vs. 1-year follow-up
  5. cIsolated lateral vs. isolated medial vs. mixed
  6. dSignificantly different (P <0.05) from the isolated lateral group when adjusted for age, sex, and body mass index as a post-hoc test of ANCOVA