Benefits of resistance exercise in lean women with fibromyalgia: involvement of IGF-1 and leptin

Table 3 Clinical response to resistance exercise among lean, overweight and obese patients

	Lean		Overweight		Obese		Differences in change
	Baseline	∆Posttest	Baseline	∆Posttest	Baseline	∆Posttest	Lean vs overweight	Lean vs obese	Overweight vs obese
	Median (IQR)	Median (IQR)	Median (IQR)	Median (IQR)	Median (IQR)	Median (IQR)
		P-value^a		P-value^a		P-value^a	P-value^b	P-value^b	P-value^b
Current pain	56 (43)	−14.5 (−25,3 to 2,8)	48 (39)	−13 (−31,5 to 13,5)	49 (17)	1 (−37,3 to 16,5)
(VAS)	n = 18	n = 18	n = 17	n = 17	n = 8	n = 8
		p = 0.039		p = 0.136		p = 0.624	p = 0.987	p = 0.429	p = 0.549
MFIGF fatigue	19 (2)	−1 (−3 to 0)	18 (4)	−1 (−2 to 1)	19 (4)	−0.5 (−2,8 to 1)
(4–20)	n = 18	n = 18	n = 17	n = 17	n = 8	n = 8
		p = 0.022		p = 0.303		p = 0.443	p = 0.757	p = 0.567	p = 0.842
Hand grip force	174 (110)	8.8 (−6,4 to 30,4)	165 (122)	10.3 (−7,5 to 41,3)	173 (144)	14 (1,4 to 35,1)
(N)	n = 18	n = 18	n = 17	n = 16	n = 8	n = 8
		p = 0.074		p = 0.098		p = 0.123	p = 0.851	p = 0.567	p = 0.881
Elbow flexion force	12.9 (5.1)	1.2 (0 to 3,6)	11.1 (7.1)	1.4 (−0,8 to 5,1)	13.5 (10.6)	3 (1,6 to 5,1)
(kg)	n = 18	n = 18	n = 17	n = 17	n = 8	n = 8
		p = 0.017		p = 0.049		p = 0.012	p = 0.858	p = 0.080	p = 0.315
Knee extension force	338 (135)	11.5 (−46,6 to 48,3)	306 (136)	43 (−31 to 74,3)	389 (185)	35.3 (−16,3 to 105,6)
(N)	n = 18	n = 18	n = 17	n = 17	n = 8	n = 8
		p = 0.647		p = 0.113		p = 0.208	p = 0.303	p = 0.285	p = 0.754

Symptom severity and strength at baseline, and change (∆) at posttest after resistance exercise. Median values with upper and lower boundaries of the interquartile range are indicated Within group comparisons (p-value^a: Wilcoxon signed rank test) and group comparisons (p-value^b: Mann–Whitney U-test) are presented. P-values in bold type are significant

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