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Table 3 Correlations of CD40 rs4810485 G > T and rs1883832 C > T polymorphisms with clinical characteristics of KOA patients

From: Single nucleotide polymorphisms in the CD40 gene associate with the disease susceptibility and severity in knee osteoarthritis in the Chinese Han population: a case-control study

Clinical characteristic

rs4810485 G > T

P

rs1883832 C > T

P

GG (44)

GT (63)

TT (26)

CC (37)

CT (75)

TT (21)

Age

   

0.858

   

0.883

  < 61 years

25 (56.82)

39 (61.90)

16 (61.54)

 

13 (61.90)

46 (61.33)

21 (56.76)

 

  ≥ 61 years

19 (43.18)

24 (38.10)

10 (38.46)

 

8 (38.10)

29 (38.67)

16 (43.24)

 

Gender

   

0.230

   

0.300

 Male

16 (36.36)

14 (22.22)

9 (34.62)

 

8 (38.10)

18 (24.00)

13 (35.14)

 

 Female

28 (63.64)

49 (77.78)

17 (65.38)

 

13 (61.90)

57 (76.00)

24 (64.86)

 

BMI (kg/m2)

   

0.107

   

0.086

 19 ≤ Y ≤ 26

33 (75)

52 (82.54)

16 (61.54)

 

12 (57.14)

59 (78.67)

30 (81.08)

33 (75)

 Y < 19 or Y > 26

11 (25)

11 (17.46)

10 (38.46)

 

9 (42.86)

16 (21.33)

7 (18.92)

11 (25)

Smoking status (%)

   

0.699

   

0.289

 Yes

10 (22.7)

11 (17.46)

4 (15.38)

 

4 (19.05)

11 (14.67)

10 (27.03)

 

 No

34 (77.3)

52 (82.54)

22 (84.62)

 

17 (80.95)

64 (85.33)

27 (72.97)

 

Alcohol consumption (%)

   

0.911

   

0.943

 Yes

17 (38.61)

22 (34.92)

9 (34.62)

 

7 (33.33)

27 (36.00)

14 (37.84)

 

 No

27 (61.36)

41 (65.08)

17 (65.38)

 

14 (66.67)

48 (64.00)

23 (62.16)

 

Heavy labor

10 (22.73)

19 (30.16)

8 (30.77)

0.653

7 (33.33)

18 (24.00)

12 (32.43)

0.534

  1. Note: CD40 Cluster of Differentiation 40, KOA Knee osteoarthritis, BMI Body mass index