Table 6 Measurements with screening and follow-up visit schedule

Informed Consent

x

Eligibility Questionnaire

x

To determine eligibility

Medical History

xc

x

x

x

x

For eligibility and to document changes in health

Risk Stratification

xc

x

Used to screen for cardiovascular risk [54]

Comorbidities Questionnaire

x

x

x

x

[55]

Randomization

x

WOMAC

x

x

x

x

Pain is primary outcome [42]

KOOS

x

x

x

x

Pain, symptoms, ADL, sport, recreation, knee QOL [56]

ICOAP

x

x

x

x

Intermittent and constant osteoarthritis pain, 2 sleep questions [57]

Cost Effectiveness

x

x

x

x

PASE scale

x

x

x

x

Physical Activity Scale for the Elderly [58]

MOCA

x

x

Montreal Cognitive Assessment [59, 60]

CES-D

x

x

x

x

The Center for Epidemiologic Studies Depression Scale [61]

EuroQol Quality of Life(EQ5D)

x

x

x

x

Quality of life measure [62]

Work History Resource

x

x

x

x

Visits to clinicians, tests, medications, injections, surgery, alternative therapies

Work Productivity and Activity Impairment Index

x

x

x

x

Assesses absenteeism and presenteeism [63]

DHQ II

x

x

x

x

NIH Diet History Questionnaire [36, 37]

SF-36

x

x

x

x

Health related quality of life [physical, mental] [64]

Self-Efficacy-Adherence

x

x

x

x

Belief can exercise over time [65]

Perceived Stress (PSS)

x

x

x

x

The degree to which people perceive their lives as stressful [66]

Pain Catastrophizing Scale (PCS)

x

x

x

x

Catastrophizing [rumination, magnification, and helplessness] [67, 68]

Healthy Literacy

x

x

x

x

Functional health literacy [69]

Walking Efficacy for Duration

x

x

x

x

Confidence in walking for different durations [65]

Gait Efficacy

x

x

x

x

Confidence in completing gait related tasks [65]

Weight Efficacy Lifestyle Questionnaire (WEL)

x

x

x

x

Self-Efficacy for weight management [70]

Positive and Negative Affect Scale (PANAS)

x

x

x

x

Positive and Negative Affect [71]

Demographics

x

Medication form

x

x

x

x

Atherosclerosis Risk in Communities form [72]

Satisfaction With Life Scale

x

x

x

x

Quality of life [73]

Height and weight

x

x

To determine BMI

Adverse Events

x

x

x

x

Also collected as they occur

Knee exam

x

To determine eligibility

Pain Severity

x

x

x

To determine MCID [74]

6 min walk

x

x

x

x

Measure of mobility [75]

Expanded Short Physical Performance Battery (SPPB)

x

x

x

x

Gait speed, sit to stand, balance tests; predicts disability [76]

Functional Leg Strength

x

x

x

x

Sit to stand test, part of SPPB

Blood Pressure

x

x

x

x

Overall health measure

GAITRite gait analysis

x

x

x

x

Temporospatial gait variables

Stair climb

x

x

x

x

Timed Stair ascent and descent [77]