Skip to main content

Table 3 Classification of functional capacity and measurement of joint changes in RA patients

From: Polymorphism and protein expression of MUTYH gene for risk of rheumatoid arthritis

 

RA patients

Chi-Square a

p value

Fisher’s Exact test a

p value

Genotype at rs3219463

G carrier - n (%)

AA - n (%)

RA Diagnosis class

 I

88 (75.2)

13 (56.5)

0.315

0.199

 II

19 (16.2)

6 (26.1)

 III

8 (6.8)

3 (13.0)

 IV

2 (1.7)

1 (4.3)

 

RA patients

T-Test a

p value

Mann–Whitney U test a

p value

Genotype at rs3219463

G carrier - n (mean ± SD)

AA - n (mean ± SD)

MUTYH serum level b

27 (20.98 ± 16.51)

13 (23.07 ± 17.16)

0.714

0.593

Joint pain

135 (31.93 ± 24.33)

28 (45.89 ± 25.46)

0.007 *

0.006 *

Joint stiffness

102 (0.62 ± 0.97)

19 (0.58 ± 0.72)

0.871

0.540

SJC 66 b

142 (1.96 ± 2.69)

26 (2.81 ± 3.18)

0.156

0.250

TJC 68 b

142 (3.83 ± 4.07)

26 (6.69 ± 7.06)

0.055

0.075

DAS 28

133 (3.88 ± 1.2)

25 (4.63 ± 1.23)

0.005 *

0.003 *

PtGA b

135 (39.65 ± 26.72)

27 (50.48 ± 27.82)

0.058

0.052

PrGA b

142 (23.73 ± 17.73)

27 (32.78 ± 23.38)

0.065

0.078

  1. a Nonparametric test
  2. b Mean value is lower in the G carrier / RA-non-risk-associated but data does not reach statistical significance
  3. * Statistically significant