From: Strontium ranelate causes osteophytes overgrowth in a model of early phase osteoarthritis
Group | D1 (n = 6, μm) | D2 (n = 6, μm) | Osteophyte size (D1-D2, n = 6, μm) | Collapsed osteophytes | ||
---|---|---|---|---|---|---|
in macroscopic samples (n = 6) | in histologic samples (n = 6) | in all samples (n = 12) | ||||
Sham | 263.62 [231.18, 296.06] | 280.26 [247.42, 313.10] | -16.64 [-39.56, 6.28] | 0 | 0 | 0 |
MNX + V | 370.19 [330.19, 410.19]* | 263.33 [234.28, 292.39] | 106.86 [46.93, 166.79]* | 1 | 0 | 1 |
MNX + SR | 445.97 [415.36, 476.58]*†| 247.79 [212.40, 283.17] | 198.18 [147.48, 248.88]*†| 5 | 2 | 7*†|