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Fig. 2 | BMC Musculoskeletal Disorders

Fig. 2

From: Agonist muscle adaptation accompanied by antagonist muscle atrophy in the hindlimb of mice following stretch-shortening contraction training

Fig. 2

The agonist PLT muscle increased muscle mass with plantarflexion SSC training whereas the antagonist TA muscle atrophied. Values for a muscle mass (normalized by tibia length) b number of muscle fibers per transverse muscle section, and c mean muscle fiber area were determined. For PLT muscles, an increase in the number of muscle fibers in cross-section accompanied the increase in mass. For TA muscles, atrophy was observed at the individual muscle fiber level. N = 9 per group with exception of total muscle fiber counts for PLT muscles. A subpopulation of all the PLT muscle sections (N = 3 to 8 per group) fulfilled the requirement for direct fiber counts – the requirement that all regions of the muscle section be free of technical defects typically incurred from prepping and cryosectioning such a relatively small muscle. Other measures (e.g. muscle fiber area) were obtained from all of the PLT muscle sections (N = 9 per group) because these relied on the sampling approach of stereological quantitative morphology. Values are means ± SE. *Different from non-trained value, P < 0.05

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