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Table 1 Reports on the effects of running exercise on articular cartilage in Wistar rats

From: Strenuous running exacerbates knee cartilage erosion induced by low amount of mono-iodoacetate in rats

Study Running distance Running period OA induced Method Effect
Sekiya et al. [5] 2009 30 km 6 weeks No   Harmful
Siebelt et al. [24] 2011 31.8 km 6 weeks No   Harmful
Beckett et al. [17] 2012 30 km / 55 km 3 / 6 weeks No   Harmful
Pap et al. [20] 1998 30 km 12 weeks Yes Intracranial self stimulation Harmful
Siebelt et al. [21] 2014 15 km 6 weeks Yes Papain injection Harmful
Saito et al. 2015 15 km 3 weeks Yes MIA 0.1 mg injection Harmful
Galois et al. [22] 2004 15 km 4 weeks Yes ACLT Beneficial
Cifuentes et al. [23] 2010 15 km 8 weeks Yes MIA 1.2 mg injection Beneficial
  1. Abbreviations: ACLT anterior cruciate ligament transection, MIA mono-iodoacetate