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Table 2 miRNA profiles of the RA patients with or without ILD

From: Plasma miRNA expression profiles in rheumatoid arthritis associated interstitial lung disease

     

ILD(+)RA

 

UIP(+)RA

 

NSIP(+)RA

 

miRNA

ILD(+)RA

UIP(+)RA

NSIP(+)RA

ILD(−)RA

P

FDR Q

P

FDR Q

P

FDR Q

hsa-miR-29c-3p

28.7 (92.4)

45.9 (121.6)

6.7 (10.4)

2.9 (2.5)

0.1772

0.6025

0.0499

0.1698

0.9334

0.9334

hsa-miR-154-5p

17.9 (59.1)

24.6 (76.8)

9.3 (21.3)

2.0 (2.8)

0.9238

0.9815

0.5331

0.7294

0.3604

0.7416

hsa-miR-543

11.0 (35.9)

14.8 (46.6)

6.1 (13.9)

1.4 (1.4)

0.4386

0.6213

0.8633

0.9173

0.1145

0.6099

hsa-miR-214-5p

8.1 (28.2)

13.6 (37.0)

1.0 (3.2)

0.2 (0.9)

0.0156

0.1322

0.0076

0.0643

0.1697

0.6099

hsa-miR-382-3p

10.9 (41.5)

14.8 (52.9)

5.8 (19.9)

0.9 (1.7)

0.4279

0.6213

0.9473

0.9473

0.1794

0.6099

hsa-let-7g-3p

29.1 (107.3)

50.3 (141.1)

1.9 (3.7)

3.3 (5.3)

0.6098

0.7974

0.5578

0.7294

0.1095

0.6099

hsa-miR-9-5p

5.8 (18.5)

9.1 (24.2)

1.5 (4.2)

0.9 (2.6)

0.8510

0.9815

0.7724

0.8753

0.4947

0.7416

hsa-miR-370-3p

12.2 (57.4)

18.2 (76.3)

4.5 (11.1)

0.3 (0.4)

0.8766

0.9815

0.3648

0.6202

0.4734

0.7416

hsa-miR-221-5p

17.1 (53.1)

26.6 (68.7)

5.0 (16.6)

0.7 (1.2)

0.3227

0.6213

0.0461

0.1698

0.5235

0.7416

hsa-miR-483-5p

80.7 (331.8)

130.5 (440.8)

16.6 (24.4)

14.3 (33.9)

0.2827

0.6213

0.2330

0.4951

0.6161

0.7888

hsa-miR-7-5p

56.2 (260.4)

91.1 (347.0)

11.5 (19.9)

4.7 (11.8)

0.0362

0.2049

0.0275

0.1559

0.2616

0.6571

hsa-miR-376b-3p

14.6 (48.8)

19.0 (63.4)

9.0 (19.3)

1.1 (1.4)

0.3718

0.6213

0.2621

0.4951

0.7915

0.8751

hsa-miR-487b-3p

12.7 (56.4)

19.1 (75.0)

4.4 (10.2)

0.5 (0.7)

0.2437

0.6213

0.1181

0.2868

0.8237

0.8751

hsa-let-7f-1-3p

24.9 (114.7)

39.8 (153.0)

5.7 (9.4)

2.6 (2.8)

0.9893

0.9893

0.6856

0.8326

0.6496

0.7888

hsa-miR-500a-5p

55.8 (230.6)

94.7 (305.3)

5.7 (12.3)

1.7 (4.6)

0.3744

0.6213

0.4566

0.7056

0.4823

0.7416

hsa-miR-582-5p

144.8 (288.5)

208.4 (360.8)

63.0 (124.4)

31.5 (60.5)

0.0693

0.2946

0.0705

0.1998

0.2706

0.6571

miRNA Index (214, 7)

0.122 (0.332)

0.202 (0.430)

0.019 (0.034)

0.006 (0.013)

0.0010

0.0162

0.0005

0.0093

0.0732

0.6099

  1. Average values of each group are shown. Standard deviations are shown in parenthesis. Differences were tested by Mann-Whitney’s U test. To correct for multiple testing, the false discovery rate Q-value was calculated
  2. RA rheumatoid arthritis, ILD interstitial lung disease, UIP Usual interstitial pneumonia, NSIP Nonspecific interstitial pneumonia, ILD(+)RA RA with ILD, UIP(+)RA RA with ILD of UIP pattern, NSIP(+)RA RA with ILD of NSIP pattern, ILD(−)RA RA without ILD