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Table 2 miRNA profiles of the RA patients with or without ILD

From: Plasma miRNA expression profiles in rheumatoid arthritis associated interstitial lung disease

      ILD(+)RA   UIP(+)RA   NSIP(+)RA  
miRNA ILD(+)RA UIP(+)RA NSIP(+)RA ILD(−)RA P FDR Q P FDR Q P FDR Q
hsa-miR-29c-3p 28.7 (92.4) 45.9 (121.6) 6.7 (10.4) 2.9 (2.5) 0.1772 0.6025 0.0499 0.1698 0.9334 0.9334
hsa-miR-154-5p 17.9 (59.1) 24.6 (76.8) 9.3 (21.3) 2.0 (2.8) 0.9238 0.9815 0.5331 0.7294 0.3604 0.7416
hsa-miR-543 11.0 (35.9) 14.8 (46.6) 6.1 (13.9) 1.4 (1.4) 0.4386 0.6213 0.8633 0.9173 0.1145 0.6099
hsa-miR-214-5p 8.1 (28.2) 13.6 (37.0) 1.0 (3.2) 0.2 (0.9) 0.0156 0.1322 0.0076 0.0643 0.1697 0.6099
hsa-miR-382-3p 10.9 (41.5) 14.8 (52.9) 5.8 (19.9) 0.9 (1.7) 0.4279 0.6213 0.9473 0.9473 0.1794 0.6099
hsa-let-7g-3p 29.1 (107.3) 50.3 (141.1) 1.9 (3.7) 3.3 (5.3) 0.6098 0.7974 0.5578 0.7294 0.1095 0.6099
hsa-miR-9-5p 5.8 (18.5) 9.1 (24.2) 1.5 (4.2) 0.9 (2.6) 0.8510 0.9815 0.7724 0.8753 0.4947 0.7416
hsa-miR-370-3p 12.2 (57.4) 18.2 (76.3) 4.5 (11.1) 0.3 (0.4) 0.8766 0.9815 0.3648 0.6202 0.4734 0.7416
hsa-miR-221-5p 17.1 (53.1) 26.6 (68.7) 5.0 (16.6) 0.7 (1.2) 0.3227 0.6213 0.0461 0.1698 0.5235 0.7416
hsa-miR-483-5p 80.7 (331.8) 130.5 (440.8) 16.6 (24.4) 14.3 (33.9) 0.2827 0.6213 0.2330 0.4951 0.6161 0.7888
hsa-miR-7-5p 56.2 (260.4) 91.1 (347.0) 11.5 (19.9) 4.7 (11.8) 0.0362 0.2049 0.0275 0.1559 0.2616 0.6571
hsa-miR-376b-3p 14.6 (48.8) 19.0 (63.4) 9.0 (19.3) 1.1 (1.4) 0.3718 0.6213 0.2621 0.4951 0.7915 0.8751
hsa-miR-487b-3p 12.7 (56.4) 19.1 (75.0) 4.4 (10.2) 0.5 (0.7) 0.2437 0.6213 0.1181 0.2868 0.8237 0.8751
hsa-let-7f-1-3p 24.9 (114.7) 39.8 (153.0) 5.7 (9.4) 2.6 (2.8) 0.9893 0.9893 0.6856 0.8326 0.6496 0.7888
hsa-miR-500a-5p 55.8 (230.6) 94.7 (305.3) 5.7 (12.3) 1.7 (4.6) 0.3744 0.6213 0.4566 0.7056 0.4823 0.7416
hsa-miR-582-5p 144.8 (288.5) 208.4 (360.8) 63.0 (124.4) 31.5 (60.5) 0.0693 0.2946 0.0705 0.1998 0.2706 0.6571
miRNA Index (214, 7) 0.122 (0.332) 0.202 (0.430) 0.019 (0.034) 0.006 (0.013) 0.0010 0.0162 0.0005 0.0093 0.0732 0.6099
  1. Average values of each group are shown. Standard deviations are shown in parenthesis. Differences were tested by Mann-Whitney’s U test. To correct for multiple testing, the false discovery rate Q-value was calculated
  2. RA rheumatoid arthritis, ILD interstitial lung disease, UIP Usual interstitial pneumonia, NSIP Nonspecific interstitial pneumonia, ILD(+)RA RA with ILD, UIP(+)RA RA with ILD of UIP pattern, NSIP(+)RA RA with ILD of NSIP pattern, ILD(−)RA RA without ILD