Covariates | Univariate analyses (sex- and age-adjusted) | Multiple analysis | ||||
---|---|---|---|---|---|---|
Odds ratio | 95% confidence intervals | P-value | Odds ratio | 95% confidence intervals | P-value | |
Age (per 1 year) | 0.97 | 0.97–0.97 | <0.001 | 0.98 | 0.97–0.98 | <0.001 |
Sex | 0.88 | 0.76–1.03 | 0.103 | 0.94 | 0.81–1.10 | 0.450 |
Comorbid conditions | ||||||
Diabetes | 0.86 | 0.69–1.09 | 0.218 | 0.96 | 0.76–1.22 | 0.758 |
Hypertension | 0.89 | 0.76–1.03 | 0.108 | 0.95 | 0.81–1.11 | 0.513 |
Ischemic heart disease | 0.73 | 0.58–0.93 | 0.009 | 0.90 | 0.70–1.15 | 0.384 |
Atrial fibrillation or flutter | 0.64 | 0.47–0.86 | 0.004 | 0.83 | 0.60–1.15 | 0.260 |
Heart failure | 0.40 | 0.28–0.58 | <0.001 | 0.47 | 0.32–0.69 | <0.001 |
Valvular disease | 0.82 | 0.53–1.27 | 0.375 | 1.11 | 0.70–1.75 | 0.657 |
Cerebrovascular disease | 0.59 | 0.43–0.82 | 0.001 | 0.65 | 0.47–0.90 | 0.010 |
Venous thromboembolic disease | 0.83 | 0.61–1.14 | 0.259 | 0.92 | 0.67–1.27 | 0.607 |
Chronic respiratory disease | 0.80 | 0.66–0.98 | 0.031 | 0.82 | 0.67–0.998 | 0.048 |
Chronic renal insufficiency | 0.43 | 0.21–0.89 | 0.022 | 0.53 | 0.25–1.09 | 0.084 |
Depression | 0.72 | 0.58–0.90 | 0.004 | 0.74 | 0.59–0.92 | 0.008 |
Malignancy | 0.66 | 0.52–0.84 | 0.001 | 0.66 | 0.52–0.84 | 0.001 |
Infections | 1.39 | 1.21–1.61 | <0.001 | 1.52 | 1.31–1.76 | <0.001 |
Fractures | 1.01 | 0.77–1.33 | 0.947 | 1.06 | 0.81–1.41 | 0.660 |
Health care consumption | ||||||
Patients hospitalizeda | 1.15 | 1.01–1.31 | 0.040 | |||
Number of inpatient admissionsa | 1.03 | 1.00–1.07 | 0.042 | |||
Cumulative days at hospitala | 0.997 | 0.99–1.00 | 0.101 | |||
Outpatient visits, secondary care | 1.06 | 1.06–1.07 | <0.001 | |||
Outpatient visits, primary care | 0.97 | 0.96–0.98 | <0.001 |