Table 1 Comparison of HRV parameter between CIA rats and controls 1^st week to 6^th week

Mean HR

(1/min)

Control

386 ± 25

411 ± 57

411 ± 6

377 ± 21

375 ± 18

378 ± 25

CIA

458 ± 35*

438 ± 31*

471 ± 31*

493 ± 4^*

383 ± 21

380 ± 28

SDNN(ms)

Control

4.53 ± 2.5

6.08 ± 3.4

3.9 ± 0.9

3.55 ± 1.3

3.89 ± 1.4

3.21 ± 1.3

CIA

8.23 ± 1.6*

12.28 ± 4.3*

5.82 ± 2.7*

4.31 ± 1.0

5.26 ± 3.4

3.21 ± 1.3

RMSSD(ms)

Control

3.03 ± 0.8

3.35 ± 1.4

2.37 ± 0.2

2.72 ± 0.5

2.81 ± 0.5

2.62 ± 0.5

CIA

3.37 ± 0.7

3.13 ± 0.5

2.73 ± 0.6

2.4 ± 0.1

2.44 ± 0.2

2.41 ± 0.1

LF(n.u)

Control

61.71 ± 9.3

60.02 ± 7.2

62.73 ± 11.1

60.29 ± 8.5

61.59 ± 7.9

59.01 ± 9.3

CIA

69.48 ± 5.7*

68.41 ± 5.1*

68.78 ± 10.1*

57.89 ± 12.7

52.13 ± 16.1

49.73 ± 16.3

HF(n.u)

Control

38.01 ± 9.1

39.85 ± 7.2

37.13 ± 11

39.38 ± 8.4

38.11 ± 7.9

40.66 ± 9.1

CIA

30.34 ± 5.6*

31.46 ± 5.0*

40.93 ± 10.1

41.77 ± 12.6

47.46 ± 15.9

49.94 ± 16.2

LF/HF

Control

1.76 ± 0.6

1.58 ± 0.5

1.9 ± 0.9

1.65 ± 0.6

1.73 ± 0.6

1.56 ± 0.6

CIA

2.41 ± 0.7*

2.24 ± 0.5*

1.68 ± 0.4

1.60 ± 0.8

1.31 ± 0.7

1.2 ± 0.8

DFA:α1

Control

0.62 ± 0.2

0.74 ± 0.3

0.69 ± 0.1

0.47 ± 0.1

0.49 ± 0.1

0.51 ± 0.1

CIA

0.88 ± 0.2*

0.82 ± 0.2*

0.7 ± 0.3

0.43 ± 0.1

0.53 ± 0.1

0.52 ± 0.1

DFA:α2

Control

0.71 ± 0.4

1.09 ± 0.3

0.84 ± 0.1

0.79 ± 0.3

0.65 ± 0.2

0.52 ± 0.3

CIA

1.12 ± 0.1⁺

1.24 ± 0.1*

0.81 ± 0.1

0.78 ± 0.1

0.62 ± 0.3

0.51 ± 0.3

DC(ms)

Control

13.7 ± 2.7

11.1 ± 3.8

9.2 ± 0.7

9.6 ± 2.9

8.2 ± 1.4

8.5 ± 3.5

CIA

9.5 ± 2.4*

9.8 ± 2.6*

7.5 ± 2.8*

6.9 ± 1.1*

6.9 ± 1.6*

7.3 ± 2.2*

AC(ms)

Control

–10.6 ± 2.4

–8.1 ± 6.3

–5.2 ± 0.4

–7.3 ± 2.7

–6.1 ± 1.4

–6.3 ± 3.1

CIA

–7.1 ± 2.6*

–7.7 ± 2.0

–4.1 ± 3.1

–4.8 ± 0.9*

–5.7 ± 1.7

–5.2 ± 1.8