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Table 6 Median differences in change of WOMAC scores and imaging parameters from baseline to follow-up

From: Assessment of subchondral bone marrow lesions in knee osteoarthritis by MRI: a comparison of fluid sensitive and contrast enhanced sequences

Method Segmentation parameter Baseline, median (range) Follow-up, median (range) p-values*
WOMACtotal N.A. 794 (76–1444) 234 (9–1782 0.023
WOMACpain N.A. 140 (18–311) 44 (3–373) 0.054
MS CEA-BML 6.5 (0–67.0) 7.5 (0–79.4) 0.21
BML 8.1 (0–70.5) 11.4 (0–86.8) 0.71
CAS CEA-BMLa 8.1 (0.1–44.9) 8.6 (1.0–81.3) 0.18
BML 5.6 (0.1–39.8) 5.3 (0.6–79.8) 0.97
Dynamika Nvoxel 29.3 (0.0–99.3) 18.8 (0.0–86.1) 0.13
MExNvoxel 379.4 (0.0–1442.1) 281.6 (0.0–1679.5) 0.13
IRExNvoxel 0.2 (0.0–3.3) 0.2 (0.0–4.1) 0.45
  1. Data was analyzed using imaging data from the entire medial knee joint. CEA-BML, BML and Nvoxel were calculated based on the relative involvement. MExNvoxel and IRExNvoxel were calculated by multiplying the absolute number of Nvoxel by ME and IRE, respectively
  2. N.A. not applicable
  3. *Changes from baseline to follow-up, Wilcoxon’s signed rank test
  4. a5 femoral and 3 tibial outliers excluded