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Table 2 Observer agreement for relative and absolute CEA-BML and STIR-BML measurements, and relative Nvoxel, irrespective of baseline/follow-up

From: Assessment of subchondral bone marrow lesions in knee osteoarthritis by MRI: a comparison of fluid sensitive and contrast enhanced sequences

Method Area Image sequence Observer agreement CEA-BML, STIR-BML and Nvoxel, relative CEA-BML, STIR-BML and Nvoxel, absolute
Biasa,% 95% CI Biasa, mm3/mm2b 95% CI
MS Femur T1 CE FS Inter-observer
Intra-observer
−0.86
−0.98
−2.68
−2.37
0.95
0.42
−79
−94
−281
−199
122
11
Tibia Inter-observer
Intra-observer
−0.67
−0.89
−4.2
−2.64
2.8
0.86
18
−58
−321
−147
358
31
Femur STIR Inter-observer
Intra-observer
−0.36
1.15
−1.45
−0.46
0.73
2.76
7
142
−129
−41
144
325
Tibia Inter-observer
Intra-observer
−0.26
1.18
−0.82
−0.06
1.35
2.41
−83
129
−209
6
44
251
CAS Femur T1 CE FS Inter-observer
Intra-observer
0.23
−0.37
−1.22
−1.03
1.68
0.29
108
−71
−59
−185
276
43
Tibia Inter-observer
Intra-observer
0.29
0.18
−1.57
−0.30
2.15
0.67
14
3
−94
−36
122
42
Femur STIR Inter-observer
Intra-observer
0.01
−0.10
−0.41
−0.42
0.43
0.21
15
67
−60
13
89
121
Tibia Inter-observer
Intra-observer
−0.10
0.22
−0.70
−0.04
0.51
0.49
−74
61
−140
28
9
94
Dynamika Femur
Tibia
DCE-MRI Intra-observer
Intra-observer
−2.75
−2.5
−4.56
−5.37
−0.94
0.37
−27
−7
−50
−29
−5
15
  1. aBland-Altman analysis
  2. bCEA-BML and STIR-BML in mm3, Nvoxel in mm2