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Table 2 Morphology and contractile properties of extensor digitorum longus muscles

From: A short-term statin treatment changes the contractile properties of fast-twitch skeletal muscles

Measure

Placebo

Lovastatin

Muscle mass; (mg)

11,89 ± 0,76

12,71 ± 0,10

Cross-sectional area; (μm2)

1154,36 ± 115,02

1285,96 ± 64,05

Twitch tension Pt; (g)

4,82 ± 0,37

6,25 ± 0,63 p=0.088

Maximal tetanic force P0; (g)

28,83 ± 2,23

30,37 ± 2,67

Specific force sP0; (g/mg)

2,45 ± 0,16

2,39 ± 0,20

Pt/P0

0,17 ± 0,01

0,20 ± 0,01

Time to peak tension TPT; (ms)

27,71 ± 1,54

29,83 ± 2,62

1/2 RT at Pt; (ms)

14,43 ± 1,14

17,00 ± 1,00

  1. The treatment with lovastatin [50 mg/kg/day] for 28 days had the tendency (0,05 < p < 0,09) to increase the twitch tension (Pt) of EDL muscles. Data are expressed as means ± SE, n = 8 mice for each experimental group. The level of significance was set at *p < 0.05