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Table 1 Morphology and contractile properties of Sol muscles

From: A short-term statin treatment changes the contractile properties of fast-twitch skeletal muscles

Measure

Placebo

Lovastatin

Muscle mass; (mg)

10,79 ± 0,10

10,92 ± 0,76

Cross-sectional area; (μm2)

1101,98 ± 78,55

1146,79 ± 88,46

Twitch tension Pt; (g)

3,25 ± 0,28

3,81 ± 0,51

Maximal tetanic force P0; (g)

22,72 ± 1,11

25,72 ± 0,45 p=0.053

Specific force sP0; (g/mg)

2,18 ± 0,09

2,38 ± 0,09

Pt/P0

0,14 ± 0,01

0,14 ± 0,02

Time to peak tension TPT; (ms)

52,14 ± 2,15

47,83 ± 3,28

1/2 RT at Pt; (ms)

47,14 ± 2,59

47,01 ± 2,30

  1. The treatment with lovastatin [50 mg/kg/day] for 28 days had the tendency (0,05 < p < 0,06) to increase the maximum tetanic force (P0) of Sol muscles. Data are expressed as means ± SE, n = 8 mice for each experimental group. The level of significance was set at *p < 0.05