Skip to main content

Table 1 Inhibition ratios of mRNA levels and protein levels

From: Lentivirus-mediated short hairpin RNA interference targeting TNF-alpha in macrophages inhibits particle-induced inflammation and osteolysis in vitro and in vivo

Particles mRNA levels mean ± SD protein levels mean ± SD (pg/ml)
  Particle Particle + TNF-LV Particle + N.C-LV IRa Particle Particle + TNF-LV Particle + N.C-LV IRa
TI 24.06 ± 5.06 11.26 ± 3.48 1.50 ± 0.57 53.22 % 780.12 ± 36.36 490.03 ± 8.80 730.06 ± 45.88 37.18 %
CE 9.01 ± 1.49 4.82 ± 0.22 1.50 ± 0.57 46.52 % 572.11 ± 38.41 329.73 ± 17.22 527.11 ± 44.68 42.37 %
  1. aIR (Inhibition ratio) = (mRNA or protein levels of Group Particle minus Group Particle + TNF-LV)/Group Particle. There were no significant differences in RNAi inhibitory effects among titanium and ceramic particle stimulation groups in both mRNA levels and protein levels (P > 0.05)