Fig. 6From: Lentivirus-mediated short hairpin RNA interference targeting TNF-alpha in macrophages inhibits particle-induced inflammation and osteolysis in vitro and in vivoThe width of the murine cranial suture was measured on the obtained orthogonal coronal images by 64-slice spiral CT. Significant reduction of cranial suture width was revealed in the Particle + TNF-LV group compared with the Particle and Particle + N.C-LV groups (P < 0.01). There was no difference between the Particle and Particle + N.C-LV groups in this parameter (P > 0.05)Back to article page