From: Identification of clinical phenotypes in knee osteoarthritis: a systematic review of the literature
 | Phenotypes | |||||
---|---|---|---|---|---|---|
Author/year | Chronic pain | Inflammatory | Metabolic syndrome | Metabolic bone/cartilage | Mechanical overload | Minimal joint disease |
Attur 2011 [18] | Â | ++ | Â | Â | Â | Â |
Bae 2010 [19] | Â | Â | Â | Â | ++ | Â |
Berry 2010a [20] | Â | Â | Â | ++ | Â | Â |
Berry 2010b [21] | Â | Â | Â | Â | Â | ++ |
Blumnenfeld 2013 [22] | Â | Â | Â | ++ | Â | Â |
Cruz-Almeida 2013 [23] | ++ | Â | Â | Â | Â | Â |
Doss 2007 [24] | Â | ++ | Â | Â | Â | Â |
Egsgaard 2015 [25] | + | Â | Â | Â | Â | Â |
Fernández-Tajes 2014 [26] |  | ++ |  |  |  |  |
Holla 2013 [27] | Â | Â | Â | Â | Â | ++ |
Jenkins 2015 [28] | Â | Â | Â | Â | Â | + |
Kerkhof 2008 [29] | Â | Â | Â | Â | Â | Â |
Kinds 2013 [9] | Â | Â | Â | Â | Â | ++ |
King 2013 [30] | + | Â | Â | Â | Â | Â |
Knoop 2011 [7] | ++ | Â | ++ | Â | ++ | ++ |
Murphy 2011 [31] | ++ | Â | Â | Â | Â | Â |
Otterness 2000 [32] | Â | ++ | Â | ++ | Â | Â |
Pereira 2013 [33] | ++ | Â | Â | Â | Â | Â |
Roemer 2012 [34] | Â | Â | Â | ++ | Â | Â |
Sowers 2002 [35] | Â | Â | ++ | Â | Â | Â |
Van der Esch 2015 [36] | ++ | Â | ++ | Â | ++ | ++ |
Van Spil 2012 [37] | Â | ++ | ++ | Â | Â | Â |
Waarsing 2015 [8] | Â | Â | Â | ++ | ++ | ++ |
Iijima 2015 [38] | Â | Â | Â | Â | + | Â |
Kittelson 2015 [40] | ++ | Â | Â | Â | Â | Â |
Total number of studies | 6 (2) | 5 | 4 | 5 | 4 (1) | 6 (1) |