Table 5 Descriptive statistics of primary outcome measured at baseline, 3-month, 9-month and 15-month after start of intervention and treatment effects as changes from baseline compared between groups

 Baseline

4.55 (2.08)

4.57 (2.08)

4.72 (2.08)

 3 month

2.62 (2.04)

2.56 (2.04)

3.97 (2.04)

−0.09

(-0.48 to 1.5)

1.17

(0.15 to 2.19)*

1.26

(0.27 to 2.25)*

 9 month

2.85 (2.04)

3.31 (2.04)

3.5 (2.07)

0.43

(-1.55 to 2.41)

0.47

(-0.52 to 1.46)

0.04

(-0.95 to 1.03)

 15 month

3.06 (2.04)

2.85 (2.04)

3.6 (2.07)

−0.24

(-2.22 to 1.74)

0.41

(-0.58 to 1.4)

0.65

(-0.34 to 1.64)

 Baseline

21.84 (10.18)

24.39 (10.18)

24.18 (10.05)

 3 month

14.62 (9.85)

14.39 (9.96)

21.74 (9.93)

−2.78

(-6.85 to 1.29)

4.78

(0.67 to 8.89)*

7.56

(3.49 to 11.63)***

 9 month

14.84 (9.85)

16.61 (9.96)

19.65 (9.93)

−0.78

(-4.87 to 3.31)

2.47

(-1.64 to 6.58)

3.25

(-0.82 to 7.32)

 15 month

15.20 (9.85)

13.80 (9.96)

17.99 (9.94)

−3.95

(-8.02 to 0.12)

0.45

(-3.64 to 4.54)

4.40

(0.35 to 8.45)*