From: Regenerate bone stimulation following limb lengthening: a meta-analysis
Authors, Year | Cohort | Number of Limbs | Mean Distraction in cm (Range) | Mean Healing Index in days/cm (± SD) | Mean Time to Fixator Removal (days) (±SD) | Mean Time to Corticalisation (days) (±SD) |
---|---|---|---|---|---|---|
Salem and Schmelz, 2014 [43] | Stimulated | 12 | 7.9 (− to -) | 33 (± −) | NR | NR |
Control | 9 | 7.9 (− to -) | 45 (± −) | NR | NR | |
El-Mowafi and Mohsen, 2005 [41] | Stimulated | 10 | 6.1 (5 to 8) | 30 (±2.96) | NR | NR |
Control | 10 | 6.1 (5 to 8) | 48 (±9.76) | NR | NR | |
Dudda et al., 2011 [40] | Stimulated | 16 | 6.6 (2.5 to 14.0) | 32.8 (±13.1) | NR | NR |
Control | 20 | 6.6 (2.5 to 14.0) | 44.4 (±6.8) | NR | NR | |
Gebauer and Correll, 2005 [42] | Stimulated | 17 | 7.06 (2.5 to 14.0) | N = 7, calcification after 6 weeks; N = 10, bridging observed after 12 weeks. | ||
Gonzalez et al., 2005 [44] | Stimulated | 30 | 11.3 (5.3 - 15.3) | NR | 308.3 (±62.82) | 279.6 (±68.4) |
Control | 30 | 11.3 (53 to 153) | NR | 339.5 (±61.17) | 313.5 (±60.6) | |
Eyres et al., 1996 [45] | Stimulated | 10 | 7.6 (− to -) | 39 (±4) | NR | NR |
Control | 8 | 7.6 (− to -) | 44 (±6) | NR | NR | |
Gold and Wasserman, 2005 [46] | Stimulated | 8 | 10.25 (8 to 14) | NR | 417.3 (± −) | NR |
Control | 12 | 9.46 (4 to 20) | NR | 501.3 (± −) | NR |