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Table 2 Specific Outcome Measures

From: Regenerate bone stimulation following limb lengthening: a meta-analysis

Authors, Year

Cohort

Number of Limbs

Mean Distraction in cm (Range)

Mean Healing Index in days/cm (± SD)

Mean Time to Fixator Removal (days) (±SD)

Mean Time to Corticalisation (days) (±SD)

Salem and Schmelz, 2014 [43]

Stimulated

12

7.9 (− to -)

33 (± −)

NR

NR

Control

9

7.9 (− to -)

45 (± −)

NR

NR

El-Mowafi and Mohsen, 2005 [41]

Stimulated

10

6.1 (5 to 8)

30 (±2.96)

NR

NR

Control

10

6.1 (5 to 8)

48 (±9.76)

NR

NR

Dudda et al., 2011 [40]

Stimulated

16

6.6 (2.5 to 14.0)

32.8 (±13.1)

NR

NR

Control

20

6.6 (2.5 to 14.0)

44.4 (±6.8)

NR

NR

Gebauer and Correll, 2005 [42]

Stimulated

17

7.06 (2.5 to 14.0)

N = 7, calcification after 6 weeks; N = 10, bridging observed after 12 weeks.

Gonzalez et al., 2005 [44]

Stimulated

30

11.3 (5.3 - 15.3)

NR

308.3 (±62.82)

279.6 (±68.4)

Control

30

11.3 (53 to 153)

NR

339.5 (±61.17)

313.5 (±60.6)

Eyres et al., 1996 [45]

Stimulated

10

7.6 (− to -)

39 (±4)

NR

NR

Control

8

7.6 (− to -)

44 (±6)

NR

NR

Gold and Wasserman, 2005 [46]

Stimulated

8

10.25 (8 to 14)

NR

417.3 (± −)

NR

Control

12

9.46 (4 to 20)

NR

501.3 (± −)

NR

  1. NR Not Reported