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Fig. 2 | BMC Musculoskeletal Disorders

Fig. 2

From: Prokineticin 2 antagonist, PKRA7 suppresses arthritis in mice with collagen-induced arthritis

Fig. 2

Changes in arthritis scores and PK2, PKR1, and PKR2 gene expression before and after the onset of arthritis. Arthritis was experimentally induced with a collagen injection on Day 21. a The severity of arthritis peaked on Day 33 and decreased thereafter. b PK2 gene expression in the joints was more elevated on Days 28 and 35 than on Day 21. c There was no significant change in PKR1 gene expression levels before and after the onset of arthritis. d PKR2 gene expression was significantly more pronounced on Days 28 and 35 than on Day 21. Values are relative to the arbitrarily assigned value of 1.0 for Day 21 and are given as means ± SEM. P values by Dunn’s multiple comparison

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