Fig. 1From: Prokineticin 2 antagonist, PKRA7 suppresses arthritis in mice with collagen-induced arthritisPKRA7 as an antagonist of PK2. PK2 binds to PKR1 and PKR2 receptors and regulates various physiological processes, including angiogenesis, chemotaxis, immune polarization, and circadian rhythm. PKRA7 also binds to PKR1 and PKR2 and competitively blocks the binding of PK2Back to article page